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25% Vitamin C + Glutathione Clinical Serum

Sensitive SkinSerum

25% Vitamin C + Glutathione Clinical Serum — Reddit Reviews

by Paula's Choice

Not enough verdicts yetSee the Reddit discussion

Updated September 13, 2026

High-derivative vitamin C and glutathione for brightening and evening skin tone.

What the community says

A 25% derivative-based vitamin C serum combined with glutathione targets dullness and uneven skin tone. It's especially suited for those with sensitive skin who can't tolerate ascorbic acid. The lightweight texture feels more like a moisturizer than a traditional serum.

From Reddit

Backed by 4 threads from r/30PlusSkinCare, r/SkincareAddiction and 1 more.

Read the threads ↓

What people love

  • High vitamin C derivative concentration avoids ascorbic acid irritation
  • Includes glutathione for antioxidant and brightening effects
  • Light moisturizer texture layers well in AM routines

Watch out for

  • Small bottle size disappoints users relative to price
  • Vitamin C actives can still cause sensitivity for some users

Product details

Key Ingredients

Skin type data limited

Where to buy

Real Reddit threads9 mentions across 4 threads

Paula's Choice 25% Vitamin C + Glutathione Clinical Serum on Reddit, in one place — 4 threads from r/30PlusSkinCare, r/SkincareAddiction and 1 more, summarized.

3. Vitamin C - Paula’s Choice 25% Vitamin C + Glutathione Clinical Serum

Positive

Morning skincare routine:

Positive

I would like to incorporate a copper peptide serum into my evening skincare routine for anti-aging.

Positive

Paula’s Choice 25% Vitamin C + Glutathione Clinical Serum

Cautionary

I ordered the smallest size but in no way was I expecting a sample size for 20$!

Cautionary

I’ll not be repurchasing from this brand.

Cautionary

Other options:

Mentioned

Paula’s Choice 25% Vitamin C + Glutathione Clinical Serum

Mentioned

Paula’s Choice 25% Vitamin C + Glutathione Clinical Serum

Mentioned

AM protocol - Cleanser, AA and Vit C, serums, moisturizer and sunscreen

Mentioned

The below are the most impactful actives I used:

Mentioned

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