
Azelaic Acid 12% Serum — Reddit Reviews
by TIRTIR
Updated October 10, 2026
Azelaic acid 12% serum that helps acne and redness; can sting.
What the community says
Studies found azelaic acid helps clear acne better than a placebo, and Redditors say this 12% serum can also calm redness and texture. The catch is the formula can feel stripping or trigger irritation for some sensitive, dehydrated faces.
What this means for you
What people love
- 12% azelaic acid with panthenol and Zinc PCA
- Helps acne, redness, and texture for a lot of users
- Watery, fast-absorbing serum that layers cleanly
Watch out for
- Can burn, dry out, and wreck the barrier for some
- Breakouts and flare-ups aren’t rare here
- Not friendly to already sensitive or dehydrated skin
Product details
Product Traits
Key Ingredients
Where to buy
What the science says vs. what Reddit says
Acne
Strong evidence
Azelaic Acid: 22 studies tested it on its own. See all 31 studies
On Reddit: 12% concentration azelaic acid serum targets pimples and prevents scarring in a week. 5 mentions
What the studies found
- Most studies found it helped clear acne
- It cleared acne better than a placebo in several studies
- It often worked about as well as tretinoin and some other common acne treatments
- Some studies found it worked less well than benzoyl peroxide or benzoyl peroxide with clindamycin
- Side effects were usually local and moderate, with fewer local side effects than tretinoin in one study
Studied at 5–20%this product: 12%
Rosacea
Strong evidence
Azelaic Acid: 17 studies tested it on its own. See all 20 studies
What the studies found
- Most studies found it helped rosacea more than a placebo
- It often reduced red bumps and redness
- It worked about as well as metronidazole, and some studies found it worked better
- Some studies found better overall skin ratings and quality of life
- Side effects were mostly mild to moderate skin reactions, such as stinging or burning, with no serious treatment-related side effects reported
Studied at 15–20%this product: 12%
Hyperpigmentation
Strong evidence
Azelaic Acid: 12 studies tested it on its own. See all 16 studies
What the studies found
- In melasma, it often made patches lighter and less widespread
- It worked about as well as hydroquinone in some studies, and better than weaker hydroquinone in others
- It also helped fade dark marks left after acne in one study
- The most common side effects were burning and stinging, and severe side effects were not reported
Studied at 15–20%this product: 12%
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 34 mentions across 25 threads
TIRTIR Azelaic Acid 12% Serum on Reddit, in one place — 25 threads from r/tretinoin, r/Rosacea and 4 more, summarized.
“TIRTIR actually has an azelaic acid serum that I’m thinking of trying next.”
Mentioned
“I’m thinking of trying next”
Mentioned
“TIRTIR actually has an azelaic acid serum”
Mentioned
“I started using Tirtir’s 12% azelaic acid and my skin agreed with it so much more.”
Positive
“It contains panthenol and zinc”
Positive
“which I think helps me tolerate it as well as not aggrevate my barrier!”
Positive
“I have been using the tir tir one and havent noticed any irritation at all and it is 12%!”
Positive
“oh this was a way better purchase for me since i have perioral dermatitis and was treating an outbreak.”
Positive
“I love the tirtir azelaic acid serum. It has improved the texture and redness on my cheeks.”
Positive
“TirTir Azaelic Acid Serum 12% - 8/10 saw a difference in a week.”
Positive
“Made my skin so soft and smooth.”
Positive
“I've been eyeing tirtir azelaic acid serum for a while now. Does it do a good job with dark spots?”
Positive
“i saw faster results with the tirtir but had to stop using it because it was too stripping and broke my barrier.”
Positive
“it was drying me out and causing my skin to flare.”
Positive
“Repurchased the Tittir one. My skin is sensitive and dehydrated, prone to redness. I've seen some good results over the months and really helps with the redness.”
Positive
“Eta: i use the tirtir 12% azelaic acid serum.”
Positive
“I have noticed that it helps shrink my pimples and once gone, the pimples don’t leave any scar pigmentation.”
Positive
“Currently using the Dr.Althea Vit C Boosting Serum 63% and the TirTir Azelaic Acid 12% Serum”
Positive





