Combination SkinAcne Spot Treatment
Azelaic Advanced — Reddit Reviews
by Regimen Lab
Updated October 9, 2026
10% azelaic acid serum for redness, texture, and post-breakout marks; expensive but elegant.
What the community says
A light azelaic acid serum with a very polished, fast-absorbing texture and no greasy film. Redditors reach for it on redness, texture, and post-breakout marks; dry or sting-prone skin should buffer carefully and expect some dryness.
What this means for you
What people love
Watch out for
Product details
Concerns
Skin Type
Product Traits
Key Ingredients
Where to buy
What the science says
Acne
Strong evidence
Azelaic Acid: 22 studies tested it on its own. See all 31 studies
What the studies found
- Most studies found it helped clear acne
- It cleared acne better than a placebo in several studies
- It often worked about as well as tretinoin and some other common acne treatments
- Some studies found it worked less well than benzoyl peroxide or benzoyl peroxide with clindamycin
- Side effects were usually local and moderate, with fewer local side effects than tretinoin in one study
Studied at 5–20%this product: 10%
Rosacea
Strong evidence
Azelaic Acid: 17 studies tested it on its own. See all 20 studies
What the studies found
- Most studies found it helped rosacea more than a placebo
- It often reduced red bumps and redness
- It worked about as well as metronidazole, and some studies found it worked better
- Some studies found better overall skin ratings and quality of life
- Side effects were mostly mild to moderate skin reactions, such as stinging or burning, with no serious treatment-related side effects reported
Studied at 15–20%this product: 10%
Hyperpigmentation
Strong evidence
Azelaic Acid: 12 studies tested it on its own. See all 16 studies
What the studies found
- In melasma, it often made patches lighter and less widespread
- It worked about as well as hydroquinone in some studies, and better than weaker hydroquinone in others
- It also helped fade dark marks left after acne in one study
- The most common side effects were burning and stinging, and severe side effects were not reported
Studied at 15–20%this product: 10%
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 27 mentions across 21 threads
Regimen Lab Azelaic Advanced on Reddit, in one place — 21 threads from r/koreanskincare, r/Rosacea and 3 more, summarized.
“* Regimen Lab Azelaic Advanced”
Positive
“Excuse me just listing the relevant products/techniques from my routine...”
Positive
“RELEVANT PRODUCTS FROM NIGHT...”
Positive
“I’m using Regimen and it doesn’t burn or anything”
Positive
“I love the regimen lab one! It blows all the other over-the-counter azelaics I've tried out of the water.”
Positive
“I do find the regimen lab tingles unless I put it on very hydrated skin though.”
Positive
“Not a cream, but the best OTC azelaic acid you can get is Regimen Lab Azelaic Advanced.”
Mentioned
“Came here looking for alternatives as well.”
Mentioned
“Anyone have any brand recs since I won't be able to purchase from dermatica anymore?”
Mentioned
“the Regimen Lab azelaic Advanced acid.”
Positive
“They’re fantastic.”
Positive
“Other than that I use Tretinoin and the Regimen Lab azelaic Advanced acid.”
Positive
“regimen lab 10/10”
Mentioned
“Regimen Labs”
Mentioned
“If you’re in Canada, the Regimen Labs one is excellent!”
Mentioned
“I just bought Remedy vitamin C and Regimen Lab azelaic acid, can’t wait to use them and have my PIE and PIH go awayyy”
Mentioned
“Give Azelaic acid a try. Anua has a good one.”
Mentioned
“What helped me most was daily sunscreen, azelaic acid”
Mentioned
