Redness/IrritationAcne Spot Treatment
Azelaic Advanced — Reddit Reviews
by Regimen Lab
Updated November 10, 2026
10% azelaic acid reduces redness and evens skin tone; HG OTC formulation.
What the community says
A 10% azelaic acid serum with potassium azeloyl diglycinate that Reddit users reach for for redness and uneven tone. It absorbs under makeup and pairs with tretinoin, though rushed application can sting and dry skin may protest.
What this means for you
Backed by 29 threads from r/30PlusSkinCare, r/koreanskincare and 3 more.
Read the threads ↓What people love
- 10% azelaic acid; OTC HG status
- Reduces redness and improves skin evenness
- Absorbs cleanly under makeup without tackiness
Watch out for
Product details
Skin Type
Product Traits
Key Ingredients
Where to buy
What the science says
Azelaic acid has strong evidence for acne, with most studies finding it cleared breakouts better than a placebo and about as well as tretinoin 1. For rosacea, where azelaic acid has strong evidence, it often reduced spots and redness, though it did not appear to help visible blood vessels 2. Azelaic acid for dark spots has some evidence, with most studies showing it lightened melasma better than a placebo, though results for sun spots were mixed 3.
- Azelaic Acid for acne Strong evidence · 31 studies
- Azelaic Acid for rosacea Strong evidence · 17 studies
- Azelaic Acid for hyperpigmentation Some evidence · 12 studies
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
How we grade researchFull ingredient list · 20
Regimen Lab Azelaic Advanced ingredients
Aqua, Azelaic Acid, Ethoxydiglycol, Sophora Japonica Root Extract, Potassium Azeloyl Diglycinate, Butylene Glycol, Glycerin, Pentylene Glycol, Methylpropanediol, Azelamide MEA, Azelamidopropyl Dimethyl Amine, Tetrasodium Tetracarboxymethyl Naringeninchalcone, Naringenin, Bisabolol, Glucosylrutin, Swertia Chirata Extract (Swertiamarin), Rutin, Houttuynia Cordata Extract, Tasmannia Lanceolata Fruit/Leaf Extract, Tetrasodium Glutamate Diacetate
Listed in label order, highest concentration first. Linked ingredients have their own page.
Real Reddit threads — 44 mentions across 29 threads
Regimen Lab Azelaic Advanced on Reddit, in one place — 29 threads from r/30PlusSkinCare, r/koreanskincare and 3 more, summarized.
“I've heard good things about the regimen lab Azealic acid - that one doesn't have salicylic acid”
Positive
“I found it so useless until I tried regimen labs 10%”
Positive
“Zero side effects and actual results (reduced redness) from the two I mentioned above.”
Positive
“* Regimen Lab Azelaic Advanced”
Positive
“Excuse me just listing the relevant products/techniques from my routine...”
Positive
“RELEVANT PRODUCTS FROM NIGHT...”
Positive
“I’m using Regimen and it doesn’t burn or anything”
Positive
“I love the regimen lab one! It blows all the other over-the-counter azelaics I've tried out of the water.”
Positive
“I do find the regimen lab tingles unless I put it on very hydrated skin though.”
Positive
“Not a cream, but the best OTC azelaic acid you can get is Regimen Lab Azelaic Advanced.”
Mentioned
“Came here looking for alternatives as well.”
Mentioned
“Anyone have any brand recs since I won't be able to purchase from dermatica anymore?”
Mentioned
“Many people recommend RegimenLab Azelaic Acid, which I'm planning to get once my skin gets better.”
Mentioned
“Are there any other OTC alternatives that you recommend?”
Mentioned
“what are we doing to get through this?”
Mentioned
“the Regimen Lab azelaic Advanced acid.”
Positive
“They’re fantastic.”
Positive
“Other than that I use Tretinoin and the Regimen Lab azelaic Advanced acid.”
Positive
