Ruboril Metroruboril A.Z — Reddit Reviews
by ISISPHARMA
Updated October 10, 2026
15% azelaic acid cream for rosacea redness and papules; sometimes stings.
What the community says
A 15% azelaic acid cream base that Redditors reach for on rosacea, redness, and papules. People like the cream texture and the no-prescription route, but dry, crepey reactions and flare-ups happen on reactive skin.
What this means for you
What people love
- 15% azelaic acid in a cream base
- Rosacea skin keeps coming up as the target
- No-prescription pharmacy buy
Watch out for
Product details
Concerns
Use caution
Product Traits
Key Ingredients
Where to buy
What the science says vs. what Reddit says
Acne
Strong evidence
Azelaic Acid: 22 studies tested it on its own. See all 31 studies
What the studies found
- Most studies found it helped clear acne
- It cleared acne better than a placebo in several studies
- It often worked about as well as tretinoin and some other common acne treatments
- Some studies found it worked less well than benzoyl peroxide or benzoyl peroxide with clindamycin
- Side effects were usually local and moderate, with fewer local side effects than tretinoin in one study
Studied at 5–20%this product: 15%
Rosacea
Strong evidence
Azelaic Acid: 17 studies tested it on its own. See all 20 studies
On Reddit: Completely dry bare skin is where users say it works best after cleansing without irritation. 7 mentions
What the studies found
- Most studies found it helped rosacea more than a placebo
- It often reduced red bumps and redness
- It worked about as well as metronidazole, and some studies found it worked better
- Some studies found better overall skin ratings and quality of life
- Side effects were mostly mild to moderate skin reactions, such as stinging or burning, with no serious treatment-related side effects reported
Studied at 15–20%this product: 15%
Hyperpigmentation
Strong evidence
Azelaic Acid: 12 studies tested it on its own. See all 16 studies
What the studies found
- In melasma, it often made patches lighter and less widespread
- It worked about as well as hydroquinone in some studies, and better than weaker hydroquinone in others
- It also helped fade dark marks left after acne in one study
- The most common side effects were burning and stinging, and severe side effects were not reported
Studied at 15–20%this product: 15%
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 23 mentions across 18 threads
ISISPHARMA Ruboril Metroruboril A.Z on Reddit, in one place — 18 threads from r/Rosacea, r/SkincareAddiction and 2 more, summarized.
“Currently, I’m trying to fix my demodex infestation so I’m following a new routine for the time being (about 25 days in).”
Positive
“AHA/BHA face wash, followed by metrorubirol AZ from isispharma, azelaic acid, and a moisturizer.”
Positive
“Unless it’s a prescription medication I keep my routine minimal as possible.”
Positive
“AA- Isispharma Metroruboril 15%”
Positive
“I then added sulfur soap and AA and it rapidly vanished.”
Positive
“I startet with 15% daily right away. I didn’t have any problems… maybe because of the Retinal?”
Positive
“I've had good results with Metroruboril from a french company, Isispharma.”
Positive
“It contains 15% Az acid and you can get it off Amazon, no prescription needed.”
Positive
“Similar here, I've had good results with Metroruboril”
Positive
“Isispharma has Metroruboril A.Z which is 15%”
Positive
“if you can get them in your country”
Positive
“My grail for rosacea skin.”
Positive
“U could look into these instead : isispharma metroburil”
Mentioned
“Also in case ure interested in trying out azealic acid i would recommend passing on the anua serum due to its formulation.”
Mentioned
“U could look into these instead : isispharma metroburil, theramid azid serum and kisocare azealic acid CREAM.”
Mentioned
“Isispharma Metroruboril AZ.”
Mentioned
“From the french pharmacy lower priced treatments include: Azeane ACM, Isispharma Teenderm AZ, Isispharma Metroruboril AZ.”
Mentioned
“If you have any suggestions, I’d really appreciate them.”
Mentioned
