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Ruboril Metroruboril A.Z

RosaceaAcne Spot Treatment

Ruboril Metroruboril A.Z — Reddit Reviews

by ISISPHARMA

82nextscore16 verdicts

Updated October 21, 2026

15% azelaic acid cream for rosacea; dramatic improvement or zero redness change.

What the community says

Backed by 57 studies

A 15% azelaic acid cream that Redditors use in rosacea routines for papules and visible redness. It can be a rosacea HG for some, yet others report dryness, crepey cheeks, or no redness improvement.

From Reddit

Backed by 18 threads from r/Rosacea, r/SkincareAddiction and 2 more.

Read the threads ↓

What people love

Watch out for

  • Does nothing for redness for some rosacea users
  • Can leave cheeks dry and crepey, with papules more inflamed

Product details

Concerns

Key Ingredients

Where to buy

What the science says vs. what Reddit says

  • Acne

    Strong evidence

    Azelaic Acid: 22 studies tested it on its own. See all 31 studies

    What the studies found
    • Most studies found it helped clear acne
    • It cleared acne better than a placebo in several studies
    • It often worked about as well as tretinoin and some other common acne treatments
    • Some studies found it worked less well than benzoyl peroxide or benzoyl peroxide with clindamycin
    • Side effects were usually local and moderate, with fewer local side effects than tretinoin in one study

    Studied at 5–20%this product: 15%

  • Rosacea

    Strong evidence

    Azelaic Acid: 15 studies tested it on its own. See all 17 studies

    On Reddit: Completely dry bare skin is where users say it works best after cleansing without irritation. 7 mentions

    What the studies found
    • Most studies found azelaic acid helped rosacea more than a placebo
    • It often reduced bumps and redness from rosacea
    • It worked about as well as metronidazole in some studies, and better in others
    • It did not seem to help visible blood vessels
    • Side effects were mainly mild to moderate, including stinging

    Studied at 15–20%this product: 15%

  • Hyperpigmentation

    Some evidence

    Azelaic Acid: 9 studies tested it on its own. See all 12 studies

    What the studies found
    • Most studies found it helped fade dark patches, especially melasma
    • It faded melasma better than a placebo in one clinical trial
    • It often worked about as well as hydroquinone, and some studies found it worked better
    • It may help dark marks left after acne, but one study found no clear benefit for sun spots
    • The most common side effects were irritation, burning and stinging

    Studied at 15–20%this product: 15%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 23 mentions across 18 threads

ISISPHARMA Ruboril Metroruboril A.Z on Reddit, in one place — 18 threads from r/Rosacea, r/SkincareAddiction and 2 more, summarized.

“Currently, I’m trying to fix my demodex infestation so I’m following a new routine for the time being (about 25 days in).”

Positive

“AHA/BHA face wash, followed by metrorubirol AZ from isispharma, azelaic acid, and a moisturizer.”

Positive

“Unless it’s a prescription medication I keep my routine minimal as possible.”

Positive

“AA- Isispharma Metroruboril 15%”

Positive

“I then added sulfur soap and AA and it rapidly vanished.”

Positive

“I startet with 15% daily right away. I didn’t have any problems… maybe because of the Retinal?”

Positive

“I've had good results with Metroruboril from a french company, Isispharma.”

Positive

“It contains 15% Az acid and you can get it off Amazon, no prescription needed.”

Positive

“Similar here, I've had good results with Metroruboril”

Positive

“Isispharma has Metroruboril A.Z which is 15%”

Positive

“if you can get them in your country”

Positive

“My grail for rosacea skin.”

Positive

“U could look into these instead : isispharma metroburil”

Mentioned

“Also in case ure interested in trying out azealic acid i would recommend passing on the anua serum due to its formulation.”

Mentioned

“U could look into these instead : isispharma metroburil, theramid azid serum and kisocare azealic acid CREAM.”

Mentioned

“Isispharma Metroruboril AZ.”

Mentioned

“From the french pharmacy lower priced treatments include: Azeane ACM, Isispharma Teenderm AZ, Isispharma Metroruboril AZ.”

Mentioned

“If you have any suggestions, I’d really appreciate them.”

Mentioned

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