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numbuzin No.2 Protein 43% Creamy Serum

Dry SkinSerum

numbuzin No.2 Protein 43% Creamy Serum — Reddit Reviews

by numbuzin

90nextscore7 verdicts

Updated November 10, 2026

Protein serum rescued tretinoin dryness and patchiness; discontinued, difficult to replace.

What the community says

A creamy, protein-heavy serum built for dry, stressed skin, with niacinamide, panthenol, ceramide NP, and cholesterol supporting a more comfortable barrier routine. Tretinoin users reach for it after flaking, but fragrance and its discontinued status complicate repurchasing.

From Reddit

Backed by 9 threads from r/AsianBeauty, r/tretinoin and 1 more.

Read the threads ↓

What people love

  • HG rescue for tretinoin-crusted dryness
  • Community holy-grail status
  • Chosen for hydration and barrier support

Watch out for

  • Discontinued, making repurchase impossible
  • Fragrance can be a deal-breaker for reactive skin

Product details

Based on limited Reddit discussion so far

Where to buy

Search on Amazon

Full ingredient list · 45

numbuzin No.2 Protein 43% Creamy Serum ingredients

Avena Sativa Kernel (Oat) Extract, Water, Cyclopentasiloxane, Butylene Glycol, Cetearyl Ethylhexanoate, Cyclohexasiloxane, Phenyl Trimethicone, Cetyl PEG/PPG-10/1 Dimethicone, Hydrogenated Poly(C6-14 Olefin), Niacinamide, Panthenol, 1,2-Hexanediol, Glycerin, Erythritol, Limnanthes Alba (Meadowfoam) Seed Oil, Sodium Chloride, Allantoin, Ethylhexylglycerin, Tocopheryl Acetate, Adenosine, Dextrin, Theobroma Cacao (Cocoa) Extract, Pantolactone, Ceramide NP, Cholesterol, Palmitic Acid, Oryza Sativa (Rice) Seed Protein Extract, Stearic Acid, Hydrolyzed Milk Protein, Lactobacillus Ferment, Glycine Soja (Soybean) Protein, Hydrolyzed Lupine Protein, Glucose, Hydrolyzed Corn Protein, Hydrolyzed Rice Protein, Hydrolyzed Soy Protein, Hydrolyzed Sweet Almond Protein, Hydrolyzed Vegetable Protein, Myristic Acid, Hydrolyzed Pea Protein, Arachidic Acid, Lauric Acid, Sodium Succinate, Disodium EDTA, Fragrance

Listed in label order, highest concentration first. Linked ingredients have their own page.

Real Reddit threads — 10 mentions across 9 threads

numbuzin numbuzin No.2 Protein 43% Creamy Serum on Reddit, in one place — 9 threads from r/AsianBeauty, r/tretinoin and 1 more, summarized.

“numbuzin no.2 protein serum”

Positive

“it was the one product i couldn’t live without.”

Positive

“Numbuzin No 2 has been my holy grail.”

Positive

“my holy grail serum that saved my dry patchy crusty skin when I had first started using Tretinoin”

Positive

“I’ve been using Numbuzin No. 2 Protein Creamy Serum”

Positive

“is no longer an option since Numbuzin stopped producing it all together”

Positive

“You should also try the numbuzin no.2 protein creamy serum.”

Mentioned

“numbuzin no 9 NAD toner”

Mentioned

“Numbuzin No 9 NAD+- entire range is just wow.”

Mentioned

“From Numbuzin, I’d look at No.2 Protein 43% Creamy Serum if hydration and barrier support are your priority.”

Positive

“It’s more about nourishing and supporting the skin rather than throwing another strong active into your routine.”

Positive

“So in your situation, I’d go No.2 first, get the dryness/barrier under control”

Positive

“Numbuzin no. 2 serum”

Positive
r/tretinoinRoutines
3

“Numbuzin no.2 creamy protein serum”

Positive

“AM: Pyunkyung Yul toner / Numbuzin no.2 creamy protein serum”

Positive

“PM: Numbuzin no.2 creamy protein serum”

Positive

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