PDRN Hyaluronic Acid 100 Moisturizing Cream — Reddit Reviews
by Anua
Updated September 23, 2026
PDRN and hyaluronic acid moisturizer for dehydrated, barrier-wrecked skin; can clog some.
What the community says
A moisturizer built around sodium DNA, hyaluronic acid, squalane, glycerin, and niacinamide for people chasing hydration and barrier support. It layers well under sunscreen and makeup, but some acne-prone users report clogged pores, extra oiliness, or breakouts.
What this means for you
What people love
- PDRN plus hyaluronic acid hydration
- Layers cleanly under sunscreen
- Fragrance-free, lightweight finish
Watch out for
- Can trigger closed comedones or cystic breakouts
- Pills under some sunscreens
- Can feel too nourishing for oily skin
Product details
Use caution
Product Traits
Key Ingredients
Where to buy
Real Reddit threads — 77 mentions across 27 threads
Anua PDRN Hyaluronic Acid 100 Moisturizing Cream on Reddit, in one place — 27 threads from r/tretinoin, r/koreanskincare and 4 more, summarized.
“On non taz nights, routine is the same except I layer on the Atobarrier OR anua PDRN hyaluronic acid moisturizing cream”
Positive
“Also here’s my full routine!! ❤️”
Positive
“I usually do 2 nights on, one night off.”
Positive
“I LOVE and will be definitely repurchasing the pdrn moisturizer, and I currently have on the pdrn and hyaluron mask”
Positive
“I really recommend them.”
Positive
“The Anua PDRN moisturiser is amazing.”
Positive
“I use Anua Hyaluronic acid 100 moisturizer.”
Positive
“PDRN literally changed my skin/hydration in less than three weeks.”
Positive
“I’d imagine other PDRN products would help with hydration as well.”
Positive
“other days between pdrn+hyalauron (anua)”
Positive
“Washing my face with cerave , rhode or aestura toners”
Positive
“Anua PDRN Hyaluronic Acid Moisturizing Cream”
Positive
“I think the PDRN is helping to keep my face more hydrated.”
Positive
“it’s a champ under sunscreen and over my serums.”
Positive
“I think the Anua 100 might work well for you. I feel like it performs best when it’s humid out.”
Mentioned
“It’s basically a combo of hyaluronic acid and Squalane moisturizer which should be acne and clog pores safe.”
Mentioned
“ANUA pdrn & hyaluronic acid cream - Honestly this texture seemed really nice, definitely plumped my skin but i would get red patches at first”
Mentioned
