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Retinal Renew 0.1% Retinaldehyde Gel

Redness/IrritationRetinoid

Retinal Renew 0.1% Retinaldehyde Gel — Reddit Reviews

by Prequel

95nextscore25 verdicts

Updated October 15, 2026

0.1% retinaldehyde smooths texture and brightens gradually; moisturizing, soothing formula.

What the community says

Backed by 9 studies

A 0.1% retinaldehyde gel for retinoid beginners seeking gradual smoothing and brightening, with ectoin, glycerin, and dimethicone making the formula unusually moisturizing. Start every third night; impatient users may find results slow, and sensitive necks still need caution.

From Reddit

Backed by 26 threads from r/AsianBeauty, r/40plusskincare and 5 more.

Read the threads ↓

What people love

  • 0.1% retinaldehyde starter strength
  • Ectoin-supported, moisturizing formula
  • Low-irritation track record, including tret-sensitive necks

Product details

Where to buy

What the science says vs. what Reddit says

  • Anti-Aging

    Some evidence

    Retinal: 5 studies tested it directly. See all 9 studies

    On Reddit: Not for acne, one user says they’re using retinal only for anti-aging benefits. 4 mentions

    What the studies found
    • Most studies found retinal helped with signs of aging
    • Studies found smoother skin and fewer wrinkles with retinal
    • Some studies found firmer, thicker skin and better elasticity
    • One study found stronger retinal improved skin tone, while both strengths improved texture and hydration
    • The reported side effects were generally mild, and studies described it as safe

    Studied at 0.05–0.1%this product: 0.1%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 30 mentions across 26 threads

Prequel Retinal Renew 0.1% Retinaldehyde Gel on Reddit, in one place — 26 threads from r/AsianBeauty, r/40plusskincare and 5 more, summarized.

“Prequel retinal”

Positive

“Prequel retinal (which i let absorb on my dry skin for 10-15 mins)”

Positive

“*two days a week I sub in Prequels milky peel for the retinal”

Positive
461

“Tretinoin/Retinaldehyde (Prequel .1%).”

Positive

“What I’m actually using:”

Positive

“I have tons of sun damage”

Positive

“You need spf and moisturizer in the daytime and either a retinal (Prequel has a good one)”

Mentioned

“For now start with those steps!”

Mentioned

“Spf is a must!!”

Mentioned
r/40plusskincareAlmost 50, need advice!
93

“A retinal serum ( Prequel seems to have good ones)”

Mentioned

“follow the instructions to build the use of it”

Mentioned

“do not just start using every night”

Mentioned

“Prequel Retinal comes in two strengths”

Mentioned

“and is formulated with ectoin, etc.”

Mentioned

“even a cosmetic retinal with soothing ingredients”

Mentioned

“or Prequel's retinal, for example.”

Mentioned

“You could try some gentler otc retinoids, like a gentle ROC retinol or Prequel's retinal”

Mentioned

“the otc products take a bit longer to work”

Mentioned

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