TNS Advanced+ Serum — Reddit Reviews
by SkinMedica
Updated July 31, 2026
Contains a potent blend of peptides and growth factors with some peer-reviewed research backing visible anti-aging…
What the community says
Peptide- and growth factor-rich serum that r/30PlusSkinCare and r/SkincareAddiction users call an anti-aging HG for dry, sensitive, and rosacea-prone skin, often used twice daily to calm redness and improve skin quality.
What this means for you
What people love
- Contains a potent blend of peptides and growth factors with some peer-reviewed research backing visible anti-aging results
- Calms redness and irritation quickly, making it one of few luxury serums that sensitive and rosacea-prone users can tolerate
- Trusted by some users to take skin from "very good to exceptional," especially when paired with professional treatments
Product details
Skin Type
Skin type data limited
Where to buy
Real Reddit threads
6 threads from r/SkincareAddiction, r/30PlusSkinCare
“OP is shilling a [$300/1oz serum](https://www.dermstore.com/skinmedica-tns-advanced-serum-1oz/12596429.html)... she's clearly in a league of her own that us plebs will never achieve.”
Mentioned
“the clearly opulent home and perfectly manicured nails with the "tip" to *just spread any residual [$300 skincare](https://www.dermstore.com/skinmedica-award-winning-system/12701672.html) to your hands*”
Mentioned
“one of my earliest memories in life is being like a 7-year-old and having a child a little bit younger than I ask "why do you have skeleton hands?”
Mentioned
“SkinMedica TNS Advanced+ Serum in combo with lasers, microneedling, and Sculptra”
Positive
“TNS Advanced+ Serum in combo with lasers, microneedling, and Sculptra”
Positive
“SkinMedica TNS Advanced+ Serum”
Positive
“I use SkinMedica TNS Advanced+ Serum, HA5 Hydra Collagen, SPF 30 sunscreen daily, and topical eye patches.”
Mentioned
“For context, I take pretty good care of my skin and overall health.”
Mentioned
“At this point, I’m wondering if this is mostly genetic or age-related, or if there are other factors I should be paying attention to.”
Mentioned
“I borrowed my mom's skinmedica TNS after a treatment and wow it did calm down my skin immediately.”
Positive
“And some peptides and growth factors do work!”
Positive
“wow it did calm down my skin immediately”
Positive
“For example, something like TNS Advanced+ Serum has peer-reviewed research and visible results.”
Mentioned
“I’m not opposed to spending money on skincare when there’s evidence behind it.”
Mentioned
“But I will never again justify paying luxury prices for products that actively made my skin worse.”
Mentioned
“There are a few expensive products I use that do really help (most notably, SkinMedica TNS Advanced+ Serum and SK-II FTE)”
Positive
“but those take my skin from very good to exceptional”
Positive
“Someone middle-aged who is trying to address multiple specific anti-aging concerns like fine lines, skin laxity, and hyperpigmentation”
Positive
