TNS Advanced+ Serum — Reddit Reviews
by SkinMedica
Updated October 10, 2026
Peptide-and-growth-factor serum that skincare Reddit treats like anti-aging HG; pricey but impressive.
What the community says
A peptide-and-growth-factor serum built for people chasing firmer, calmer-looking skin and real anti-aging payoff. Redditors with dry, sensitive, or post-procedure skin report visible improvement, but the $300-ish price tag makes it a hard splurge.
What this means for you
Backed by 18 threads from r/30PlusSkinCare, r/scacjdiscussion and 5 more.
Read the threads ↓What people love
Watch out for
Product details
Where to buy
Real Reddit threads — 35 mentions across 18 threads
SkinMedica TNS Advanced+ Serum on Reddit, in one place — 18 threads from r/30PlusSkinCare, r/scacjdiscussion and 5 more, summarized.
“Skinmedica TNS has strong research.”
Mentioned
“For topicals, I’d go for research- based peptides”
Mentioned
“These may soften the look of your marionette lines a bit”
Mentioned
“TNS Advanced 😭”
Positive
“TNS Advanced+ Serum”
Positive
“TNS”
Positive
“SkinMedica TNS Advanced+ Serum in combo with lasers, microneedling, and Sculptra”
Positive
“TNS Advanced+ Serum in combo with lasers, microneedling, and Sculptra”
Positive
“SkinMedica TNS Advanced+ Serum”
Positive
“Epidermal growth factors. I almost never hear anyone on the skincare subs talk about it, but it's made my skin look 10x better than tretinoin ever did.”
Positive
“within a couple weeks my skin was radiant.... like I hadn't seen since childhood.”
Positive
“THIS. The skinmedica TNS serum is soooooo good!”
Positive
“I use SkinMedica TNS Advanced+ Serum, HA5 Hydra Collagen, SPF 30 sunscreen daily, and topical eye patches.”
Mentioned
“For context, I take pretty good care of my skin and overall health.”
Mentioned
“I use SkinMedica TNS Advanced+ Serum...”
Mentioned
“And some peptides and growth factors do work!”
Positive
“I borrowed my mom's skinmedica TNS after a treatment and wow it did calm down my skin immediately.”
Positive
“That said, there are certain ingredients that can make a genuinely noticeable difference.”
Positive
