De La Cruz is best known for its Sulfur Ointment, popular for being an affordable, straightforward acne treatment rooted in traditional sulfur therapy. The community appreciates its effectiveness on stubborn acne at a budget-friendly price point, making it a go-to for those looking for a simple, no-frills spot treatment. However, some users report that it can be drying or cause irritation, and its strong sulfur scent isn't for everyone.