Compare · Retinoids
Retrinal 0.1% Intensive Multi-Corrective Cream vs Differin Adapalene Gel 0.1%: which is better?
One leans gentler and more cushiony, while the other is the acne workhorse with a harsher learning curve.
The quick answer
Depends what you need
- Rated higher: Retrinal 0.1% Intensive Multi-Corrective Cream — 85 vs 78 nextscore
- More reviewed: Adapalene Gel 0.1% — 919 vs 21 verdicts
Avene suits people prioritizing a gentler, cushioned retinoid feel; Differin suits people focused on acne clearing and pore congestion, even with more irritation.
Choose Retrinal 0.1% Intensive Multi-Corrective Cream if
- you want a gentler retinoid feel
- your skin is sensitive
Choose Differin Adapalene Gel 0.1% if
- you want acne and blackhead help
- you can tolerate dryness and purging

Avene
Retrinal 0.1% Intensive Multi-Corrective Cream
See alternatives$2.30/ml · 29.6 ml

At a glance
| Retrinal 0.1% Intensive Multi-Corrective Cream | Differin Adapalene Gel 0.1% |
|---|---|
| $2.30/ml | — |
| 85 · 21 verdicts | 78 · 919 verdicts |
| — | Adapalene |
What Reddit says
Retrinal 0.1% Intensive Multi-Corrective Cream
What Reddit likes
- Retinal without prescription drama
- Often reads as super gentle
- Hydrating, cushiony cream base
Watch out for
- .1% can feel downright potent
- Not cheap for a retinoid
- Sensitive eyes and skin can still react
Differin Adapalene Gel 0.1%
What Reddit likes
- OTC retinoid strength without a prescription
- Clears clogged pores and blackheads
- Less brutal than tret for some skin
Watch out for
- Purge can last 6-12 weeks
- Dries skin out hard
- Eye-area irritation and dry eyes are common complaints
Compare full ingredient lists · 1 in common
In both · 1
- Sodium Hydroxide
Only in Retrinal 0.1% Intensive Multi-Corrective Cream · 24
- Avene Thermal Spring Water (Avene Aqua)
- Caprylic/Capric Triglyceride
- Glycerin
- Squalane
- Butyrospermum Parkii (Shea) Butter (Butyrospermum Parkii Butter)
- Carthamus Tinctorius (Safflower) Seed Oil (Carthamus Tinctorius Seed Oil)
- Pentaerythrityl Tetracaprylate/Tetracaprate
- Cetearyl Alcohol
- Behenyl Alcohol
- Niacinamide
- C20-22 Alkyl Phosphate
- C20-22 Alcohols
- Acacia Senegal Gum
- Adenosine
- Cetearyl Glucoside
- Helianthus Annuus (Sunflower) Seed Oil (Helianthus Annuus Seed Oil)
- Red 33 (CI 17200)
- Retinal
- Sodium Benzoate
- Sodium Hyaluronate
- Terminalia Chebula Fruit Extract
- Tocopherol
- Tocopheryl Glucoside
- Xanthan Gum
Only in Differin Adapalene Gel 0.1% · 7
- Adapalene
- Carbomer 940
- Edetate Disodium
- Methylparaben
- Poloxamer 182
- Propylene Glycol
- Purified Water