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Medik8 Liquid Peptides vs Multi-Peptide + HA Serum: which is better?

This comparison comes down to softening smile lines versus adding hydration for skin that feels dehydrated.

The quick answer

Depends what you need

  • Rated about the same — 89 vs 89 nextscore

Medik8 Liquid Peptides focuses on softening smile lines, while The Ordinary Multi-Peptide + HA Serum offers extra hydration for dehydrated skin.

Choose Medik8 Liquid Peptides if

  • you want to soften smile lines
  • you want a serum to slot into a tretinoin routine

Choose Multi-Peptide + HA Serum if

  • your skin feels dehydrated and you want extra plumping hydration
  • you prefer a budget-friendly, one-step serum

At a glance

Medik8 Liquid PeptidesMulti-Peptide + HA Serum
$2.30/ml$0.54/ml
89 · 23 verdicts89 · 33 verdicts
Peptides bothPeptides both, Hyaluronic Acid

What Reddit says

Medik8 Liquid Peptides

What Reddit likes

  • Broad multi-peptide lineup
  • Plumps skin and softens smile lines
  • Works in tretinoin sandwich routines

Watch out for

  • Expensive, with benefits fading when skipped
  • Not acne-safe for everyone
  • Can feel heavy on oily T-zones
See the Reddit threads on Medik8 Liquid Peptides

Multi-Peptide + HA Serum

What Reddit likes

  • Multiple peptides with extra plumping hydration
  • Budget-friendly, one-step serum
  • Frequently slotted into tretinoin routines

Watch out for

  • Visible changes may take six months
  • Many users find the anti-aging payoff negligible
  • Can trigger breakouts or irritation with frequent use
See the Reddit threads on Multi-Peptide + HA Serum
Compare full ingredient lists · 18 in common

In both · 18

  1. Aqua (Water)
  2. Glycerin
  3. Butylene Glycol
  4. Phenoxyethanol
  5. Sodium Hyaluronate
  6. Acetyl Hexapeptide-8
  7. Palmitoyl Tripeptide-1
  8. Palmitoyl Tetrapeptide-7
  9. Palmitoyl Tripeptide-38
  10. Pentapeptide-18
  11. Sodium Lactate
  12. Hydroxypropyl Cyclodextrin
  13. Carbomer
  14. Xanthan Gum
  15. Ethylhexylglycerin
  16. Caprylyl Glycol
  17. Polysorbate 20
  18. Citric Acid

Only in Medik8 Liquid Peptides · 13

  1. Carnosine
  2. Inulin
  3. Alpha-Glucan Oligosaccharide
  4. Palmitoyl Pentapeptide-4
  5. Tetrapeptide-21
  6. Acetyl Tetrapeptide-5
  7. Copper Palmitoyl Heptapeptide-14
  8. Palmitoyl Sh-Hexapeptide-13 Serine SP Amide
  9. PPG-13-Decyltetradeceth-24
  10. Lactic Acid/Glycolic Acid Copolymer
  11. Polyvinyl Alcohol
  12. Glyceryl Caprylate
  13. Phenylpropanol

Only in Multi-Peptide + HA Serum · 33

  1. Lactococcus Ferment Lysate
  2. Dipeptide Diaminobutyroyl Benzylamide Diacetate
  3. Acetylarginyltryptophyl Diphenylglycine
  4. Sodium Hyaluronate Crosspolymer
  5. Allantoin
  6. Glycine
  7. Alanine
  8. Serine
  9. Valine
  10. Isoleucine
  11. Proline
  12. Threonine
  13. Histidine
  14. Phenylalanine
  15. Arginine
  16. Aspartic Acid
  17. Trehalose
  18. Fructose
  19. Glucose
  20. Maltose
  21. Urea
  22. Sodium PCA
  23. PCA
  24. Sodium Chloride
  25. Sodium Hydroxide
  26. Pentylene Glycol
  27. Acacia Senegal Gum
  28. PPG-26-Buteth-26
  29. PEG-40 Hydrogenated Castor Oil
  30. Trisodium Ethylenediamine Disuccinate
  31. Ethoxydiglycol
  32. Sodium Benzoate
  33. Chlorphenesin

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