
Amino Acids + B5 — Reddit Reviews
by The Ordinary
Updated September 3, 2026
5% panthenol and amino acids hydrate, calm irritation, and repair skin barrier.
What the community says
This serum combines 5% panthenol with 17% amino acids to hydrate and soothe skin effectively. It is favored by tretinoin users for calming irritation and repairing the skin barrier. The texture can feel a bit greasy, which some dislike.
What this means for you
What people love
- 5% panthenol and 17% amino acids for hydration and barrier repair
- Calms redness and irritation for tretinoin users
- Usable AM and PM, often applied immediately after cleansing
Watch out for
- Greasy texture can be off-putting for some users
- May feel heavy for those preferring lighter serums
- Contains vitamin C; possible caution for sensitive skin
Product details
Skin Type
Where to buy
Real Reddit threads — 26 mentions across 15 threads
The Ordinary Amino Acids + B5 on Reddit, in one place — 15 threads from r/AsianBeauty, r/scacjdiscussion and 3 more, summarized.
“I only use Aestura 365 hydro essence/The ordinary amino acid B5 with it when my skin is in super bad drying condition.”
Positive
“The ordinary amino acid B5”
Positive
“when my skin is in super bad drying condition”
Positive
“The Ordinary Amino Acids + B5 (5% panthenol, 17% amino acids)”
Mentioned
“# Disclosed Panthenol %”
Mentioned
“The Ordinary Amino Acids + B5”
Mentioned
“Give Amino Acid B5 serum a try.”
Positive
“I use this before applying tretinoin and it has been such a game changer .”
Positive
“Since I've been using AA I wake up with calm hydrated skin”
Positive
“I apply TO amino acid B5 serum. Wait 10-15 mins then apply tret.”
Positive
“Morning: Rotate the ordinary Hyaluronic acid 2% + B5 and amino acid + B5”
Positive
“For years I’ve been using The Ordinary”
Positive
“When mine was damaged I used TO amino acid B5 serum,”
Positive
“My barrier healed within 2 days.”
Positive
“When mine was damaged I used TO amino acid B5 serum, TO barrier support serum, TO rice lipids emulsion then TO phytoceramides moisturizer.”
Positive





