Argireline Solution 10% — Reddit Reviews
by The Ordinary
Updated October 29, 2026
Acetyl Hexapeptide-8 targets expression lines; temporary results demand consistent twice-daily use.
What the community says
A watery peptide serum centered on Acetyl Hexapeptide-8 for forehead lines, crow’s feet, and other expression creases. It suits people wanting a low-cost, Botox-adjacent experiment, but results are temporary, inconsistent, and sometimes nonexistent.
What this means for you
What people love
Watch out for
- Temporary cosmetic effect, not a permanent wrinkle fix
- YMMV is extreme; some users see nothing after months
- Can trigger breakouts for some acne-prone users
Product details
Concerns
Product Traits
Key Ingredients
Where to buy
What the science says vs. what Reddit says
Anti-Aging
Some evidence
Peptides: 3 studies tested it directly. See all 5 studies
On Reddit: Stubborn 11s get targeted twice daily between the brows, with users reporting noticeable improvement. 36 mentions
What the studies found
- All 3 studies that tested peptides directly found they helped with signs of aging
- Studies found peptides improved wrinkles, firmness, and skin texture
- One study found a peptide serum reduced crow’s feet and forehead wrinkles more than retinol
- One study found peptides improved firmness and texture more than a growth-factor serum, though wrinkle changes were small
- The reported side effects were stinging and itching, and none were reported in one study
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 81 mentions across 27 threads
The Ordinary Argireline Solution 10% on Reddit, in one place — 27 threads from r/tretinoin, r/30PlusSkinCare and 4 more, summarized.
“The Ordinary are Argireline 10% age defense solution with Vitamin C powder and ferulic acid powder mixed in”
Positive
“The same serum as in the morning but without the vitamin C”
Positive
“I then use Biassance repair moisturizer mix with a little bit of good molecules facial oil.”
Positive
“I think maybe the argireline helped immensely as well.”
Positive
“I think the argireline helped make it less tense and relaxed the area.”
Positive
“Use argireline to forehead, and any other wrinkle area”
Positive
“Ordinary Argireline serum + Ordinary Eye Peptide serum”
Mentioned
“applied in that order around the eye area”
Mentioned
“Alternatively — Ordinary Argireline serum + Ordinary Eye Peptide serum (applied in that order around the eye area).”
Mentioned
“The Ordinary Argireline+HA serum is very affordable and has helped my mother’s wrinkles a lot”
Positive
“If you want, try that Argireline serum.”
Positive
“use on lightly damp skin, eg right out of the shower”
Positive
“For Argireline I took a tip from another redditor to use a spray pump since it’s so watery.”
Mentioned
“I’d read that the NIOD pumps fit The Ordinary bottles...”
Mentioned
“I had an empty Ordinary bottle and brought it with me to eyeball what would fit.”
Mentioned
“Argireline and matrixyl 3000 are great peptides to help minimize lines if u want to hold off on botox.”
Positive
“Im using them and have noticed significant improvement in as little as 4 weeks.”
Positive
“Highly recommend!”
Positive
Dupes & Alternatives
Often paired with
Products Redditors use alongside this one
The Ordinary
Mentioned together in 10 threads
“I use Argireline 10% serum and Matrixyl 10% + HA both from The Ordinary and they help my 11s.”