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Argireline Solution 10%

Anti-AgingSerum

Argireline Solution 10% — Reddit Reviews

by The Ordinary

92nextscore37 verdicts

Updated October 17, 2026

Acetyl hexapeptide-8 temporarily softens expression lines; consistency beats instant results.

What the community says

Backed by 6 studies

A watery acetyl hexapeptide-8 serum for forehead, brow, and crow’s-feet expression lines, especially if Botox is off the table. Expect cosmetic, temporary smoothing rather than wrinkle reversal; inconsistent use and diminishing results frustrate some routines.

From Reddit

Backed by 27 threads from r/tretinoin, r/30PlusSkinCare and 4 more.

Read the threads ↓

What people love

  • Visible forehead-line softening with consistent use
  • Watery serum that layers easily
  • Targets dynamic lines without injectable treatment

Watch out for

  • Results are temporary, not permanent wrinkle correction
  • Does nothing for some users
  • Can trigger breakouts

Product details

Where to buy

What the science says vs. what Reddit says

  • Anti-Aging

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Peptides: 2 studies tested it on its own. See all 6 studies

    On Reddit: Dynamic lines get twice-daily attention around the brow and crow’s feet, with consistency key to seeing results. 29 mentions

    What the studies found
    • Both studies that tested it on its own found it helped with signs of aging
    • Studies found it improved firmness and made skin texture look smoother
    • One study found it reduced wrinkles and improved how much water the skin held
    • One study found it worked better than a human-derived growth factor serum for skin texture and firmness
    • No stinging, itching, or discomfort was reported in one study

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 68 mentions across 27 threads

The Ordinary Argireline Solution 10% on Reddit, in one place — 27 threads from r/tretinoin, r/30PlusSkinCare and 4 more, summarized.

“The Ordinary are Argireline 10% age defense solution with Vitamin C powder and ferulic acid powder mixed in”

Positive

“The same serum as in the morning but without the vitamin C”

Positive

“I then use Biassance repair moisturizer mix with a little bit of good molecules facial oil.”

Positive

“I think maybe the argireline helped immensely as well.”

Positive

“I think the argireline helped make it less tense and relaxed the area.”

Positive

“Use argireline to forehead, and any other wrinkle area”

Positive

“Ordinary Argireline serum + Ordinary Eye Peptide serum”

Mentioned

“applied in that order around the eye area”

Mentioned

“Alternatively — Ordinary Argireline serum + Ordinary Eye Peptide serum (applied in that order around the eye area).”

Mentioned

“The Ordinary Argireline+HA serum is very affordable and has helped my mother’s wrinkles a lot”

Positive

“If you want, try that Argireline serum.”

Positive

“use on lightly damp skin, eg right out of the shower”

Positive

“For Argireline I took a tip from another redditor to use a spray pump since it’s so watery.”

Mentioned

“I’d read that the NIOD pumps fit The Ordinary bottles...”

Mentioned

“I had an empty Ordinary bottle and brought it with me to eyeball what would fit.”

Mentioned
274

“Argireline and matrixyl 3000 are great peptides to help minimize lines if u want to hold off on botox.”

Positive

“Im using them and have noticed significant improvement in as little as 4 weeks.”

Positive

“Highly recommend!”

Positive

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