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Azelaic Acid Derivative Complex 10%

Combination SkinSerum

Azelaic Acid Derivative Complex 10% — Reddit Reviews

by Naturium

82nextscore10 verdicts

Updated September 25, 2026

Niacinamide plus azelaic derivative for redness, pores, and brown spots; YMMV.

What the community says

Backed by 41 studies

A lightweight azelaic-derivative serum with niacinamide that people slot into AM or PM routines for redness, pores, and hyperpigmentation. Redditors like the pump and how it sits under makeup. Niacinamide-sensitive rosacea skin can hate it.

From Reddit

Backed by 11 threads from r/scacjdiscussion, r/AsianBeauty and 4 more.

Read the threads ↓

What people love

Watch out for

  • Niacinamide can sting rosacea-prone skin
  • Doesn't budge redness or pores for everyone
  • Can feel like it does nothing at first

Product details

Skin type data limited

Where to buy

Search on Amazon

What the science says

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it on its own. See all 17 studies

    What the studies found
    • Most studies found niacinamide helped acne
    • Some studies found 4% niacinamide cleared acne about as well as clindamycin
    • One study found 4% niacinamide improved red, sore spots, but IPL worked better
    • Some research found no clear difference, and a large review said the effects were uncertain
  • Hyperpigmentation

    Some evidence

    Niacinamide: 5 studies tested it on its own. See all 24 studies

    What the studies found
    • All of these studies found niacinamide helped fade dark spots or patches
    • In clinical trials, 5% niacinamide faded dark spots more than a placebo
    • It also helped when used with salicylic acid peels, more than peels alone
    • Used on its own, it helped, but one study found a niacinamide mix worked better
    • One study found the fading effect reversed after stopping niacinamide

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 16 mentions across 11 threads

Naturium Azelaic Acid Derivative Complex 10% on Reddit, in one place — 11 threads from r/scacjdiscussion, r/AsianBeauty and 4 more, summarized.

“Naturium’s Azelaic Topical Acid 10% does not even contain actual Azelaic Acid (it’s a derivative).”

Cautionary

“And then there are companies that just lie.”

Cautionary

“So why should we just ‘trust the company?’”

Cautionary

“Kinda AB, the Naturium azelaic acid has done wonders for the KP on the face (cheeks).”

Positive

“the Naturium azelaic acid has done wonders for the KP on the face (cheeks).”

Positive

“Next I tried Naturium azelaic acid 10% and I saw a huge improvement within 2 days of use.”

Positive

“Azelaic Topical Acid 10% from Naturium brand.”

Positive

“This is the first thing that has worked for decreasing redness and pores.”

Positive

“I’ve been using Naturium azelaic acid and have seen improvement in my hyperpigmentation”

Positive

“I love the one from Naturium!”

Positive

“It feels hydrating and dries really nicely on my skin”

Positive
31

“I like the naturium one.”

Mentioned

“What’s the best AA product you’ve found”

Mentioned

“I like The Inkey List”

Mentioned

“Have you recently started the Naturium Azelaic Acid? It contains niacinamide, which is an irritant to a lot of people, especially people with Rosacea.”

Cautionary

“AM - wash off ivermectin using baby shampoo or the tower 28 daily balancing gel cleanser, dry, natrium azelaic topical acid 10%, dry, then throughout the day tower 28 daily rescue facial spray.”

Cautionary

“This is how my face looked like when I finally figured out that Niacinamide was destroying my skin.”

Cautionary

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