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345 Relief Cream

Skin BarrierMoisturizer

345 Relief Cream — Reddit Reviews

by Dr. Althea

80nextscore337 verdicts

Updated November 10, 2026

Niacinamide-led gel-cream fades marks and calms redness; clogging complaints persist.

What the community says

Backed by 53 studies

A watery gel-cream with niacinamide, panthenol, ceramide NP, and tea tree leaf water, built for lightweight barrier support and calmer-looking redness. It suits oily or combination skin and layers neatly under makeup, though clog-prone users report closed comedones.

From Reddit

Backed by 23 threads from r/tretinoin, r/koreanskincare and 2 more.

Read the threads ↓

What people love

  • Fast-absorbing gel-cream; excellent under makeup
  • Niacinamide helps fade post-acne marks
  • Comfortable barrier support for oily, combination skin

Watch out for

Product details

What TikTok says

Skip to videos

From 13 TikTok videos2 sponsored, marked with outlined numbers

Several creators say the lightweight cream is soothing and suits acne-prone or irritated skin 12345. Pharmacists disagree on its strength: one says it isn't enough for deep repair 67, while another rates it 5/10 for barrier science 3. Sponsored creators say it suits irritated skin, while the 147 Barrier Cream is richer for dry skin 28.

Sponsored means the creator disclosed a brand partnership or the video ran as a paid ad.

Videos open on TikTok in a new tab.

“oh but very lightweight very good for acne really good moisturizer”
“The 345 Relief Cream is the one I reach for when my skin is feeling irritated, breaking out, looking red”
“it's lightweight and better for post acne and blemish care”
“A solid moisturizing cream that's still gentle enough for acne prone skin.”
See all 13 TikTok videos (11 unsponsored) →

How to use it

From Reddit routines

What the science says

Niacinamide has some evidence for helping acne, with most studies finding it helped and often working about as well as clindamycin applied to the skin 1. Niacinamide has some evidence for fading dark spots, as all four direct studies found it helped them fade 2. Niacinamide has some evidence for signs of aging, with studies showing firmer skin, fewer wrinkles, and better water retention 3. For the skin barrier, one study found less water loss, but that evidence is not proven yet and is thin 4.

  1. Niacinamide for acne Some evidence · 17 studies
  2. Niacinamide for hyperpigmentation Some evidence · 17 studies
  3. Niacinamide for anti-aging Some evidence · 8 studies
  4. Niacinamide for skin barrier Not proven yet · 17 studies

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

How we grade research

Full ingredient list · 38

Dr. Althea 345 Relief Cream ingredients

Aqua (Water), Melaleuca Alternifolia (TEA Tree) Leaf Water, Propanediol, Glycerin, 1,2-Hexanediol, Hydrogenated Polydecene, Vinyl Dimethicone, C14-22 Alcohols, Niacinamide, Caprylic/Capric Triglyceride, Panthenol, Dicaprylyl Carbonate, Butylene Glycol, Ammonium Acryloyldimethyltaurate/Vp Copolymer, Caprylyl Methicone, Polymethylsilsesquioxane, C12-20 Alkyl Glucoside, Hydroxyacetophenone, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Polyquaternium-51, Ethylhexylglycerin, Tromethamine, Sodium Hyaluronate, Sodium Stearoyl Glutamate, Coptis Japonica Root Extract, Centella Asiatica Leaf Water, Beta-Glucan, Resveratrol, Hydrolyzed Hyaluronic Acid, Camellia Sinensis Leaf Water, Tocopherol, Madecassoside, Sodium DNA, Centella Asiatica Extract, Ceramide Np, Tannic Acid, Disodium EDTA, Sodium Phytate

Listed in label order, highest concentration first. Linked ingredients have their own page.

Real Reddit threads — 684 mentions across 23 threads

Dr. Althea 345 Relief Cream on Reddit, in one place — 23 threads from r/tretinoin, r/koreanskincare and 2 more, summarized.

“after that, i use dr. althea 345 relief cream”

Positive

“It’s very lightweight.”

Positive

“it’s lightweight, hydrating, and layers really well with the rest of my routine.”

Positive

“Dr. Althea 345 Relief Cream: This cream is more watery than the other ones.”

Positive

“It’s also gentle, moisturizing and odorless.”

Positive

“The Dr. Althea cream does feel more like a lotion than cream!”

Positive

“So far I've gotten: Dr. Althea 345 Cream”

Positive

“At this point they are my #1 source, with exceptions for sunscreen, and a few HG's, every time I go the selection gets better and better.”

Positive

“What have you found, and what do you think about k-beauty in costco?”

Positive

“- Dr. Althea 345 Relief Cream”

Positive

“I really like the Dr Athena 345, it was my intro into Korean skincare.”

Positive

“I’ve gone through a few tubes already of the 345 but I feel like it’s just ok, but my skin tolerates it and it doesn’t break me out”

Positive
507

“Dr. Althea 345 moisturizer ($29.99 after rebate, normally $39.99)”

Positive

“Wow I spent $22 for a single 345 moisturizer! That’s incredible”

Positive

“The dr Althea moisturizer is amazing”

Positive

“VT reedleshot + Dr. Althea 345 has been pretty good at removing my acne dark spots.”

Positive

“i have it and love for my oily skin but 345 cream has saved me”

Positive

“my routine is Skin1004 ampoule foam cleanser, the skin1004 ampoule and i also have the soothing gel but i use 345 cream more”

Positive

Dupes & Alternatives

Compare all 12 alternatives

Often paired with

Products Redditors use alongside this one

  • Skin1004 Madagascar Centella Asiatica Ampoule

    Skin1004

    Madagascar Centella Asiatica Ampoule

    Mentioned together in 11 threads

    “Then Skin1004 Madagascar Centella Asiatica Ampoule. Next: COSRX Advanced Snail 96 Mucin Power Essence. Moisturizer: Aveeno Calm + Restore Oat Gel or Dr. Althea 345 Relief Cream.”

    — r/SkincareAddiction

  • COSRX Advanced Snail 96 Mucin Power Essence

    COSRX

    Advanced Snail 96 Mucin Power Essence

    Mentioned together in 6 threads

    “AM - cerave oil cleanser, pair cream, snail mucin, 345 cream, BoJ spf”

    — r/AsianBeauty

  • Vaseline Original Healing Jelly

    Vaseline

    Original Healing Jelly

    Mentioned together in 5 threads

    “I only put Vaseline at night and once I got a handle on the rashes (after a couple weeks) I would put Dr Althea 345 relief cream after showers.”

    — r/eczema

  • Vanicream Gentle Facial Cleanser

    Vanicream

    Gentle Facial Cleanser

    Mentioned together in 5 threads

    “pm: bioderma micellar water, vanicream gentle cleanser, naturie hatomugi skin conditioner, skin1004 centella ampoule, iunik beta glucan, dr althea 345 relief cream”

    — r/acne

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