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345 Relief Cream

Skin BarrierMoisturizer

345 Relief Cream — Reddit Reviews

by Dr. Althea

80nextscore322 verdicts

Updated October 30, 2026

Niacinamide gel-cream calms redness and supports barrier; closed-comedone risk.

What the community says

Backed by 53 studies

A lightweight niacinamide gel-cream with panthenol, centella, beta-glucan, and ceramide NP, built for daytime hydration and redness-prone combination skin. It layers neatly under sunscreen, though clog-prone or reactive users report closed comedones, burning, and flare-ups.

From Reddit

Backed by 25 threads from r/tretinoin, r/koreanskincare and 2 more.

Read the threads ↓

What people love

  • Lightweight gel-cream for oily-combination skin
  • Calms redness and supports damaged barriers
  • Layers cleanly under makeup and sunscreen

Watch out for

Product details

How to use it

From Reddit routines

What the science says vs. what Reddit says

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it directly. See all 17 studies

    On Reddit: For hormonal breakouts, one user says it helped pimples heal faster and prevented post-acne scarring. 44 mentions

    What the studies found
    • Most studies found niacinamide helped acne
    • It often worked about as well as clindamycin when put on the skin
    • Some studies found it reduced red, sore spots and other pimples
    • Some research found the results were uncertain or showed no clear difference
  • Hyperpigmentation

    Some evidence

    Niacinamide: 4 studies tested it directly. See all 17 studies

    On Reddit: Post-acne pigmentation gets praise from a user without active acne, who says it helps, though others report breakouts. 14 mentions

    What the studies found
    • All 4 studies that tested it directly found it helped fade dark spots or patches
    • It reduced facial dark spots better than a moisturizer without niacinamide
    • Women with chloasma saw darker patches improve more when nicotinamide was added to salicylic acid
    • Studies also found facial skin looked lighter as dark spots faded
  • Anti-Aging

    Some evidence

    Niacinamide: 2 studies tested it directly. See all 8 studies

    What the studies found
    • Both studies that tested it directly found it helped with signs of aging
    • It improved how firm and elastic the skin looked
    • It reduced wrinkles, uneven tone, redness, and yellowing
    • It helped skin hold more water and lowered water loss through the skin
  • Skin Barrier

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Niacinamide: 1 study tested it directly. See all 17 studies

    On Reddit: Oily, acne-prone routines get a lighter, gel-like cream often used in the morning without a sticky feel. 114 mentions

    What the studies found
    • The one study that tested it directly found it helped the skin barrier
    • It lowered water loss through the skin
    • It increased the thickness of the outer layer of skin

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 651 mentions across 25 threads

Dr. Althea 345 Relief Cream on Reddit, in one place — 25 threads from r/tretinoin, r/koreanskincare and 2 more, summarized.

“after that, i use dr. althea 345 relief cream”

Positive

“It’s very lightweight.”

Positive

“it’s lightweight, hydrating, and layers really well with the rest of my routine.”

Positive

“Dr. Althea 345 Relief Cream: This cream is more watery than the other ones.”

Positive

“It’s also gentle, moisturizing and odorless.”

Positive

“The Dr. Althea cream does feel more like a lotion than cream!”

Positive

“So far I've gotten: Dr. Althea 345 Cream”

Positive

“At this point they are my #1 source, with exceptions for sunscreen, and a few HG's, every time I go the selection gets better and better.”

Positive

“What have you found, and what do you think about k-beauty in costco?”

Positive

“- Dr. Althea 345 Relief Cream”

Positive

“I really like the Dr Athena 345, it was my intro into Korean skincare.”

Positive

“I’ve gone through a few tubes already of the 345 but I feel like it’s just ok, but my skin tolerates it and it doesn’t break me out”

Positive
507

“Dr. Althea 345 moisturizer ($29.99 after rebate, normally $39.99)”

Positive

“Wow I spent $22 for a single 345 moisturizer! That’s incredible”

Positive

“The dr Althea moisturizer is amazing”

Positive

“VT reedleshot + Dr. Althea 345 has been pretty good at removing my acne dark spots.”

Positive

“i have it and love for my oily skin but 345 cream has saved me”

Positive

“my routine is Skin1004 ampoule foam cleanser, the skin1004 ampoule and i also have the soothing gel but i use 345 cream more”

Positive

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