
Dermatological Cream — Reddit Reviews
by E45
Updated October 13, 2026
Paraffin-rich barrier cream for eczema flares; mixed results on irritated faces.
What the community says
A basic emollient cream built around white soft paraffin and light liquid paraffin for sealing in moisture during dry-skin flares. Eczema users often reach for it, but facial irritation and no benefit for perioral dermatitis are recurring deal-breakers.
What this means for you
What people love
Watch out for
- Can sting freshly irritated skin
- No help reported for some eczema or facial cases
- Facial redness may persist despite use
Product details
Skin Type
Skin type data limited
Where to buy
Real Reddit threads — 8 mentions across 6 threads
E45 Dermatological Cream on Reddit, in one place — 6 threads from r/eczema and r/30PlusSkinCare, summarized.
“HaVe yOu TrIeD e45 cReAM? IT cLeAReD iT uP fOr mY fRiEnD.”
Mentioned
“It's even better the person working say "This is the best stuff for eczema, it works great”
Mentioned
“HeLpS rEdUcE fLaRe UpS”
Mentioned
“my mom still brings me things like an e45 cream saying it worked when i was a toddler so maybe itll help again.”
Positive
“what worked well for me and what didnt, and what worked in certain weathers, what foods etc.”
Positive
“my mom and i both have eczema”
Positive
“as did the E45 cream I put on after, but went that quickly subsided.”
Positive
“Stung like a mother at first, as did the E45 cream I put on after”
Positive
“Then you moisturise after?”
Positive
“Have you tried E45 Dermatological Cream Treatment?”
Mentioned
“that product has been recommended to me for moisture barrier assistance.”
Mentioned
“I've heard really good things about this product.”
Mentioned
“I was prescribed doxycycline and E45 cream and neither helped at all!”
Cautionary
“it was very sore, weeping and crusty and awful to look at”
Cautionary
“neither helped at all!”
Cautionary
“Have you tried an even more basic moisturiser? I use E45 cream.”
Positive
“IME my skin fares better with as short an ingredient list as possible.”
Positive
“if something has much more than like...petroleum-derived stuff, lanolin, glycerin, fatty alcohols, and preservatives, my skin pitches a fit.”
Positive





