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Liquid Peptides

Anti-AgingSerum

Liquid Peptides — Reddit Reviews

by Medik8

89nextscore23 verdicts

Updated October 16, 2026

Multi-peptide serum plumps skin and softens smile lines; pricey, benefits fade quickly.

What the community says

Backed by 6 studies

A 30% multi-peptide serum with sodium hyaluronate, built for mature or tretinoin-treated skin wanting a plumper look without a harsh active. It feels cosmetically elegant, but the $68 price and quickly fading payoff frustrate skeptics.

From Reddit

Backed by 30 threads from r/30PlusSkinCare, r/SkincareAddiction and 5 more.

Read the threads ↓

What people love

  • Broad multi-peptide lineup
  • Plumps skin and softens smile lines
  • Works in tretinoin sandwich routines

Watch out for

  • Expensive, with benefits fading when skipped
  • Not acne-safe for everyone
  • Can feel heavy on oily T-zones

Product details

Where to buy

What the science says vs. what Reddit says

  • Anti-Aging

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Peptides: 2 studies tested it on its own. See all 6 studies

    On Reddit: Between-boob chest wrinkles show a noticeable difference, but it fades quickly after a night or two off. 9 mentions

    What the studies found
    • Both studies that tested it on its own found it helped with signs of aging
    • Studies found it improved firmness and made skin texture look smoother
    • One study found it reduced wrinkles and improved how much water the skin held
    • One study found it worked better than a human-derived growth factor serum for skin texture and firmness
    • No stinging, itching, or discomfort was reported in one study

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 37 mentions across 30 threads

Medik8 Liquid Peptides on Reddit, in one place — 30 threads from r/30PlusSkinCare, r/SkincareAddiction and 5 more, summarized.

“Since then, I added the following to my routine: -medik8 advanced mp liquid peptides”

Positive

“Crazy,I have .1 tret. Medik8 peptides and have had the alastin in my cart for a while”

Positive

“Seeing improvement in smile lines after 6 months”

Positive

“The Geek & Gorgeous peptide serum is really good and compares well to medik8 liquid peptides.”

Mentioned

“Any substitute for The Ordinary's Multi-Peptide Copper Serum?”

Mentioned

“I've been using Maelove Peptide Squad with copper”

Mentioned

“I've also been using the stupidly expensive Medik8 liquid peptides more recently”

Positive

“it seems to be making a noticeable difference in my between-boob chest wrinkles.”

Positive

“if I skip a night or two, it reverts quickly”

Positive

“I’ve been using medik8 Bakuchiol and their multi peptide serum”

Positive

“I’m halfway through both bottles and my skin is looking better than it has in awhile.”

Positive

“Medicube pink peptides serum, not a patch on my medik8 liquid peptides”

Mentioned

“my medik8 liquid peptides (which is too expensive)”

Mentioned

“not a patch on my medik8 liquid peptides”

Mentioned

“I have extremely sensitive skin and found that the only things that work for my skin are: ... Medik8 liquid peptides”

Positive

“it improved my skin tenfold.”

Positive

“the only things that work for my skin are”

Positive

Dupes & Alternatives

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Compared with

Reddit's best serums by concern or ingredient list

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