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Mela B3 Dark Spot Serum

HyperpigmentationSerum

Mela B3 Dark Spot Serum — Reddit Reviews

by La Roche-Posay

67nextscore28 verdicts

Updated October 22, 2026

Niacinamide dark-spot serum with occasional wins; results often stall on stubborn pigmentation.

What the community says

Backed by 53 studies

This is a niacinamide-focused serum for post-acne marks, sunspots, and melasma routines. Redditors report visible fading after consistent use, yet others see nothing after months; burning also shows up, making patch-testing sensible for reactive skin.

From Reddit

Backed by 27 threads from r/SkincareAddiction, r/30PlusSkinCare and 3 more.

Read the threads ↓

What people love

  • Four months of nightly use produced noticeable reduction for some users
  • Fits tretinoin routines; three-minute dry-down and less post-tret peeling reported

Watch out for

  • Many users see no difference after one bottle or three months
  • Burning sensation reported immediately after application
  • Stubborn sunspots and specific hyperpigmentation can resist it

Product details

Where to buy

What the science says vs. what Reddit says

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it on its own. See all 17 studies

    What the studies found
    • Most studies found niacinamide helped acne
    • It often cleared acne about as well as clindamycin when put on the skin
    • Some studies found it helped reduce red, sore spots and pimples
    • Some evidence is still uncertain because some studies found no clear difference
  • Hyperpigmentation

    Some evidence

    Niacinamide: 4 studies tested it on its own. See all 17 studies

    On Reddit: Nightly use over four months brought one commenter a great reduction in dark spots. 12 mentions

    What the studies found
    • All 4 studies that tested it on its own found it helped fade dark spots
    • It reduced facial dark spots better than a moisturizer without niacinamide
    • Some studies found skin looked lighter as dark spots faded
    • When used with salicylic acid, it improved dark patches more than salicylic acid alone
  • Anti-Aging

    Some evidence

    Niacinamide: 2 studies tested it on its own. See all 8 studies

    What the studies found
    • Both studies that tested it on its own found it helped with signs of aging
    • It improved how firm and elastic the skin looked
    • It reduced wrinkles and uneven tone, including spots, redness, and yellowing
    • It helped the skin hold more water and reduced water loss through the skin
  • Skin Barrier

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Niacinamide: 1 study tested it on its own. See all 17 studies

    What the studies found
    • The one study that tested it on its own found it helped the skin barrier
    • It lowered water loss through the skin
    • It increased the thickness of the outer skin layer

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 42 mentions across 27 threads

La Roche-Posay Mela B3 Dark Spot Serum on Reddit, in one place — 27 threads from r/SkincareAddiction, r/30PlusSkinCare and 3 more, summarized.

“and la roche posay mela b3 every morning”

Positive

“My skincare routine is basically cleaning my face with micelar water, effaclar by la roche posay and biretix every other day at night, and la roche posay mela b3 every morning.”

Positive

“I wear sunscreen every day.”

Positive

“PM: Cleanser (La Roche-Posay Toleriane) → La Roche-Posay Mela B3 serum → La Roche-Posay Cicaplast Gel B5”

Positive

“Open to hearing if this is doing anything useful for the post-AK redness/damage, or if I should be adding/swapping something.”

Positive

“Anything you'd add to or change about my current routine, or anything you'd specifically make sure to ask my derm about at my next visit?”

Positive

“La Roche Posay Mela B3 serum, then wait at least 3 minutes for it to absorb/dry”

Positive

“My skin has had near-zero post-tret peeling since I've started this regimen”

Positive

“Gentle tips that have helped me while re-implementing tret into my PM regimen”

Positive

“La Roche posay mela B3 serum works wonders for dark spots ..... Good luck babe!”

Positive

“Does anyone know what these brown marks are under my eyes and how I can get rid of them?”

Positive

“Hi! Does anyone know what these brown marks are under my eyes and how I can get rid of them?”

Positive

“[La Roche Posay Mela B3 serum ]”

Mentioned

“Evening:”

Mentioned

“Some examples of products that may help:”

Mentioned
82

“3. La Roche Posay mela B3 serum (for dark spot correction)”

Positive

“My skincare routine tonight is as follows”

Positive

“Everything but the pair acne cream is apart of my normal routine so I will know if the pair is the thing making the difference.”

Positive

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