nextbest

See what everyone's saying

Ruboril Metroruboril A.Z

RosaceaAcne Spot Treatment

Ruboril Metroruboril A.Z — Reddit Reviews

by ISISPHARMA

83nextscore17 verdicts

Updated October 29, 2026

15% azelaic acid reduces redness and papules for some rosacea users; reactions vary.

What the community says

Backed by 57 studies

A 15% azelaic acid cream that Redditors use for rosacea redness and papules, often applied to completely dry skin. It suits people wanting a higher-strength, non-prescription azelaic acid step, but some report crepey dryness and more inflamed papules.

From Reddit

Backed by 19 threads from r/Rosacea, r/SkincareAddiction and 2 more.

Read the threads ↓

What people love

Watch out for

  • Triggered red, inflamed papules for some users
  • Made cheeks dry and crepey despite sandwiching
  • Did not reduce redness for some users

Product details

Concerns

Key Ingredients

Where to buy

What the science says vs. what Reddit says

  • Acne

    Strong evidence

    Azelaic Acid: 22 studies tested it directly. See all 31 studies

    What the studies found
    • Most studies found azelaic acid helped clear acne
    • It often cleared acne better than a placebo
    • It usually worked about as well as tretinoin
    • It sometimes worked less well than benzoyl peroxide-based treatment
    • Side effects were usually local and moderate, with fewer local side effects than tretinoin in one trial

    Studied at 5–20%this product: 15%

  • Rosacea

    Strong evidence

    Azelaic Acid: 15 studies tested it directly. See all 17 studies

    On Reddit: Visible redness and papules ease for one user, who applies it to completely dry, bare skin without irritation. 8 mentions

    What the studies found
    • Most studies found it helped with rosacea more than a placebo or some other treatments
    • It often reduced bumps and redness from rosacea
    • It worked about as well as metronidazole in some studies, and better in others
    • It did not seem to help visible blood vessels
    • Reported side effects were mainly mild to moderate

    Studied at 15–20%this product: 15%

  • Hyperpigmentation

    Some evidence

    Azelaic Acid: 9 studies tested it directly. See all 12 studies

    What the studies found
    • Most studies found it helped fade dark spots or patches, especially melasma
    • It often lightened melasma better than a placebo
    • It worked about as well as hydroquinone in some studies, and better in others
    • Results were mixed for other pigment concerns, with no benefit seen for some sun spots
    • The most common side effects were irritation, burning and stinging

    Studied at 15–20%this product: 15%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 23 mentions across 19 threads

ISISPHARMA Ruboril Metroruboril A.Z on Reddit, in one place — 19 threads from r/Rosacea, r/SkincareAddiction and 2 more, summarized.

“Currently, I’m trying to fix my demodex infestation so I’m following a new routine for the time being (about 25 days in).”

Positive

“AHA/BHA face wash, followed by metrorubirol AZ from isispharma, azelaic acid, and a moisturizer.”

Positive

“Unless it’s a prescription medication I keep my routine minimal as possible.”

Positive

“AA- Isispharma Metroruboril 15%”

Positive

“I then added sulfur soap and AA and it rapidly vanished.”

Positive

“I startet with 15% daily right away. I didn’t have any problems… maybe because of the Retinal?”

Positive

“Metroruboril by ISISPHARMA – The best azelaic acid-based product I've discovered.”

Positive

“I've had good results with Metroruboril from a french company, Isispharma.”

Positive

“It contains 15% Az acid and you can get it off Amazon, no prescription needed.”

Positive

“Similar here, I've had good results with Metroruboril”

Positive

“Isispharma has Metroruboril A.Z which is 15%”

Positive

“if you can get them in your country”

Positive

“My grail for rosacea skin.”

Positive

“U could look into these instead : isispharma metroburil”

Mentioned

“Also in case ure interested in trying out azealic acid i would recommend passing on the anua serum due to its formulation.”

Mentioned

“U could look into these instead : isispharma metroburil, theramid azid serum and kisocare azealic acid CREAM.”

Mentioned

Dupes & Alternatives

Compare all 12 alternatives

Reddit's best acne spot treatments by concern or ingredient list

We use cookies to improve your experience. Learn more