
Ruboril Metroruboril A.Z — Reddit Reviews
by ISISPHARMA
Updated October 29, 2026
15% azelaic acid reduces redness and papules for some rosacea users; reactions vary.
What the community says
A 15% azelaic acid cream that Redditors use for rosacea redness and papules, often applied to completely dry skin. It suits people wanting a higher-strength, non-prescription azelaic acid step, but some report crepey dryness and more inflamed papules.
What this means for you
What people love
- Cream-base 15% azelaic acid
- Redditors report visibly less redness and fewer papules
- Some users start daily without irritation
Watch out for
- Triggered red, inflamed papules for some users
- Made cheeks dry and crepey despite sandwiching
- Did not reduce redness for some users
Product details
Concerns
Use caution
Product Traits
Key Ingredients
Where to buy
What the science says vs. what Reddit says
Acne
Strong evidence
Azelaic Acid: 22 studies tested it directly. See all 31 studies
What the studies found
- Most studies found azelaic acid helped clear acne
- It often cleared acne better than a placebo
- It usually worked about as well as tretinoin
- It sometimes worked less well than benzoyl peroxide-based treatment
- Side effects were usually local and moderate, with fewer local side effects than tretinoin in one trial
Studied at 5–20%this product: 15%
Rosacea
Strong evidence
Azelaic Acid: 15 studies tested it directly. See all 17 studies
On Reddit: Visible redness and papules ease for one user, who applies it to completely dry, bare skin without irritation. 8 mentions
What the studies found
- Most studies found it helped with rosacea more than a placebo or some other treatments
- It often reduced bumps and redness from rosacea
- It worked about as well as metronidazole in some studies, and better in others
- It did not seem to help visible blood vessels
- Reported side effects were mainly mild to moderate
Studied at 15–20%this product: 15%
Hyperpigmentation
Some evidence
Azelaic Acid: 9 studies tested it directly. See all 12 studies
What the studies found
- Most studies found it helped fade dark spots or patches, especially melasma
- It often lightened melasma better than a placebo
- It worked about as well as hydroquinone in some studies, and better in others
- Results were mixed for other pigment concerns, with no benefit seen for some sun spots
- The most common side effects were irritation, burning and stinging
Studied at 15–20%this product: 15%
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 23 mentions across 19 threads
ISISPHARMA Ruboril Metroruboril A.Z on Reddit, in one place — 19 threads from r/Rosacea, r/SkincareAddiction and 2 more, summarized.
“Currently, I’m trying to fix my demodex infestation so I’m following a new routine for the time being (about 25 days in).”
Positive
“AHA/BHA face wash, followed by metrorubirol AZ from isispharma, azelaic acid, and a moisturizer.”
Positive
“Unless it’s a prescription medication I keep my routine minimal as possible.”
Positive
“AA- Isispharma Metroruboril 15%”
Positive
“I then added sulfur soap and AA and it rapidly vanished.”
Positive
“I startet with 15% daily right away. I didn’t have any problems… maybe because of the Retinal?”
Positive
“Metroruboril by ISISPHARMA – The best azelaic acid-based product I've discovered.”
Positive
“I've had good results with Metroruboril from a french company, Isispharma.”
Positive
“It contains 15% Az acid and you can get it off Amazon, no prescription needed.”
Positive
“Similar here, I've had good results with Metroruboril”
Positive
“Isispharma has Metroruboril A.Z which is 15%”
Positive
“if you can get them in your country”
Positive
“My grail for rosacea skin.”
Positive
“U could look into these instead : isispharma metroburil”
Mentioned
“Also in case ure interested in trying out azealic acid i would recommend passing on the anua serum due to its formulation.”
Mentioned
“U could look into these instead : isispharma metroburil, theramid azid serum and kisocare azealic acid CREAM.”
Mentioned





