
P-TIOX Anti-Wrinkle Serum — Reddit Reviews
Updated October 18, 2026
Peptide serum for fine-line softening and glow; results vary sharply.
What the community says
A peptide serum for people chasing a Botox-adjacent look without immediately reaching for injections. Redditors report glow and softer fine lines, often after several weeks, though others used three bottles with no visible improvement.
What this means for you
What people love
Watch out for
- Slow payoff; one user needed two months
- Three bottles did nothing for one user
- Irritation reports led some users to stop it
Product details
Concerns
Skin Type
Product Traits
Key Ingredients
Where to buy
What the science says vs. what Reddit says
Acne
Some evidence
Niacinamide: 6 studies tested it on its own. See all 17 studies
Hyperpigmentation
Some evidence
Niacinamide: 4 studies tested it on its own. See all 17 studies
What the studies found
Anti-Aging
Some evidence
Niacinamide: 2 studies tested it on its own. See all 8 studies
On Reddit: Lines Botox cannot tackle get attention here, with one user also praising the glow. 5 mentions
Skin Barrier
Not proven yet
Few or mixed studies. This claim isn't established.
Niacinamide: 1 study tested it on its own. See all 17 studies
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 31 mentions across 15 threads
SkinCeuticals P-TIOX Anti-Wrinkle Serum on Reddit, in one place — 15 threads from r/30PlusSkinCare, r/tretinoin and 4 more, summarized.
“I’ve used SkinCeuticals P-tiox after getting Botox and I find it helps with lasting longer!”
Positive
“I also checked and it seems to have the same ingredients that others mentioned (argireline, peptides).”
Positive
“after getting Botox”
Positive
“I am scared about putting tret too close to my eyes, but I find that Skinceuticals P-Tiox helps a tiny bit.”
Positive
“those lines are always the first to return when I need another round of injections.”
Positive
“I am scared about putting tret too close to my eyes”
Positive
“use VitC + P-tiox from SkinCeuticals. My holy grail.”
Positive
“Literally makes my skin glow and helps with fine lines that Botox cannot tackle.”
Positive
“And in that order are the first two products I use on my face in the morning after washing.”
Positive
“Skinceuticals P-Tiox”
Positive
“Vitamin C- Skinceuticals CE Ferulic”
Positive
“Avene Cicalfate cream”
Positive
“My routine consists of tret, prequel multi quench, Skinceuticals HA intensifier multi Glycan, Skinceuticals PTIOX...”
Positive
“despite my intense skincare routine, my under eyes just continue to look like cracked mud.”
Positive
“not all at once of course and not all things on the same day”
Positive
“i introduced this and skinceuticals ptiox this week, had some irritation”
Mentioned
“so laid off the ptiox, assumed it was that.”
Mentioned
“Now I'm wondering!”
Mentioned





