nextbest

See what everyone's saying

Niacinamide 10% + TXA 4% Serum

HyperpigmentationSerum

Niacinamide 10% + TXA 4% Serum — Reddit Reviews

by Anua

64nextscore78 verdicts

Updated October 16, 2026

Redditors report dark-spot fading; studies found 10% niacinamide reduced pimples.

What the community says

Backed by 77 studies

A 10% niacinamide and 4% tranexamic acid serum targeting dark marks, with arbutin and multiple hyaluronic acid forms. Redditors report impressive fading, while studies found 10% niacinamide can reduce pimples; sensitive, acne-prone users report breakouts and barrier damage.

From Reddit

Backed by 29 threads from r/30PlusSkinCare, r/AsianBeauty and 4 more.

Read the threads ↓

What people love

Watch out for

Product details

Where to buy

What the science says vs. what Reddit says

  • Hyperpigmentation

    Strong evidence

    Tranexamic Acid: 16 studies tested it on its own. See all 21 studies

    On Reddit: Melasma users report a huge improvement in dark spots, making this a targeted pick for stubborn patches. 39 mentions

    Both ingredients for hyperpigmentation

    Tranexamic Acid Strong evidence

    • Most studies found it helped fade dark patches, especially in melasma
    • It often worked about as well as hydroquinone or vitamin C
    • It could work better when used with microneedling or laser than those treatments alone
    • Different forms helped, including pills, skin treatments, and injections
    • The most common side effects were stomach upset, skin irritation, and menstrual changes

    Studied at 1–5%this product: 4%

    Niacinamide Some evidence

    5 studies tested it on its own. See all 20 studies

    • All 5 studies that tested it on its own found it helped fade dark spots
    • On its own, it reduced facial darkening and made skin look lighter than a placebo
    • It also improved dark spots linked with sun damage in one clinical trial
    • Used with other ingredients, it faded patches more than niacinamide alone or the other ingredient alone
    • The side effects were similar and mild in the study that reported them

    Studied at 2–10%this product: 10%

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it on its own. See all 17 studies

    On Reddit: Oily T-zones reach for it to control oil and target dark spots from acne scars. 5 mentions

    What the studies found
    • Most studies found niacinamide helped acne
    • It often cleared acne about as well as clindamycin when put on the skin
    • Some studies found it helped reduce red, sore spots and pimples
    • Some evidence is still uncertain because some studies found no clear difference

    Studied at 4–10%this product: 10%

  • Anti-Aging

    Some evidence

    Niacinamide: 3 studies tested it on its own. See all 9 studies

    What the studies found
    • All 3 studies that tested it on its own found it helped with signs of aging
    • Studies found it improved the look of wrinkles and made skin seem firmer
    • Studies also found it helped dark spots and reduced redness and yellowing
    • One study found it helped skin hold more water and lowered water loss through the skin
    • Used with another ingredient, it improved dark spots, fine lines, wrinkles, and firmness more than niacinamide alone

    Studied at 2–5%this product: 10%

  • Skin Barrier

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Niacinamide: 1 study tested it on its own. See all 17 studies

    What the studies found
    • The one study that tested it on its own found it helped the skin barrier
    • It lowered water loss through the skin
    • It increased the thickness of the outer skin layer

    Studied at 4–5%this product: 10%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 153 mentions across 29 threads

Anua Niacinamide 10% + TXA 4% Serum on Reddit, in one place — 29 threads from r/30PlusSkinCare, r/AsianBeauty and 4 more, summarized.

“tranexamic Anua 10% plus niacinimide”

Positive

“These are the main ones I have stuck with”

Positive

“I really saw a big difference after I introduced the tranexamic”

Positive

“Night: tretinoin (retin-a 0.1%), tranexemic (Anua), azelaic (Naturium)”

Positive

“The tranexemic is meant to help with pigmentation/dark spots which I always get after I get a pimple 🥲”

Positive

“the main actives I always have in my routine are tretinoin, vitamin c, azelaic acid, and tranexemic acid.”

Positive

“their 10% niacinamide + 4% TXA serum”

Cautionary

“to spot treat PIE”

Cautionary

“a few weeks later started developing closed comedones around the areas I applied.”

Cautionary

“Anua txa niacinamide serum”

Cautionary

“it’s so sticky and just sits on my skin”

Cautionary

“I really don’t understand the hype”

Cautionary

“I have some melasma and the anua dark spot corrector (10% niamicide 4% txa) has made a huge improvement”

Positive

“for me it’s made a huge difference”

Positive

“I fell for their TikTok/Insta marketing and got their niacinamide serum... It broke me out and destroyed my skin barrier within one use :(”

Positive

“I haven't tried anything from Anua.”

Mentioned

“Love both of these products!”

Mentioned

“And I use that Anua serum a couple times a week, it’s a staple for me :)”

Mentioned

Dupes & Alternatives

Compare all 12 alternatives

Compared with

Reddit's best serums by concern, skin type or ingredient list

We use cookies to improve your experience. Learn more