Madecassoside Tetrasome Cica Cream — Reddit Reviews

• Acne

  Some evidence

  Niacinamide: 6 studies tested it on its own. See all 17 studies→

  What the studies found

  • Most studies found niacinamide helped acne
  • It often cleared acne about as well as clindamycin
  • Some studies found fewer red, sore spots with 4% niacinamide
  • Some evidence was uncertain, and some studies found no clear difference

• Hyperpigmentation

  Some evidence

  Niacinamide: 5 studies tested it on its own. See all 24 studies→

  What the studies found

  • All of these studies found niacinamide helped fade dark spots or patches
  • Niacinamide 5% faded dark spots more than a placebo in studies of sun-damaged skin and dark patches
  • Used with salicylic acid peels, niacinamide improved dark patches more than peels alone
  • A niacinamide mix faded dark spots better than niacinamide alone in one study
  • One study found the fading effect reversed after niacinamide was stopped

• Skin Barrier

  Not proven yet

  Few or mixed studies. This claim isn't established.

  Niacinamide: 1 study tested it on its own. See all 17 studies→

  What the studies found

  • All studies found it helped the skin barrier
  • It lowered water loss through the skin
  • It made the outer layer of skin thicker

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.