TXA Niacinamide 15 Serum — Reddit Reviews
by Medicube
Updated August 1, 2026
High 15% niacinamide boosts barrier and targets redness alongside tranexamic acid for pigmentation
What the community says
Tranexamic acid plus 15% niacinamide serum targeted at hyperpigmentation that r/AsianBeauty often pairs with other actives but can be drying or irritating for sensitive and rosacea-prone skin.
What this means for you
What people love
- High 15% niacinamide boosts barrier and targets redness alongside tranexamic acid for pigmentation
- Frequently layered AM with tretinoin to support fading dark spots and melasma
- Gentle enough to be used daily but some find results require 6-8 weeks
Watch out for
- Can cause irritation or flare-ups in sensitive or rosacea-prone skin, especially combined with vitamin C or glycolic acid
- Some users report dryness or itchiness, needing additional hydration or skipping the serum periodically
- Evidence of mixed efficacy — noticeable hyperpigmentation improvement is often slow or subtle
Product details
Skin type data limited
Where to buy
Real Reddit threads
8 threads from r/tretinoin, r/koreanskincare +2 more
“Apply Medicube TXA 15% Serum”
Positive
“I was also introducing Tranexamic Acid serum during the daytime to boost the hyperpigmentation fighting effects of the tret. It has worked well for me though.”
Positive
“Hope this is of use to someone!”
Positive
“5. Medicube TXA 15%”
Positive
“The medicube TX serum is really good when paired with the toowongfoo for hyperpigmentation.”
Positive
“The medicube & twowongfoo are for the hyperpigmentation”
Positive
“I usually follow with medicube txa niacinamide and moisturizer.”
Positive
“Instead of the txa niacinamide, i used good molecules HA serum and mositurizer.”
Positive
“Did this for 2 months and it actually made the clogging worse.”
Positive
“I have some hyperpigmentation and started using medicubes TXA serum in the mornings.”
Mentioned
“Too soon to tell if it’s improving things but I’m hopeful.”
Mentioned
“I am going to buy the 16% from medicube as the one I’m currently using is running out and is quite expensive 😬”
Mentioned
“as the one I’m currently using is running out”
Mentioned
“You can ask your derm for 0.3 Adapalene. But first you need to tolerate 0.1 daily with just the moisture blanket”
Mentioned
“Medicube TXA Serum (only introduced last week to deal with hyperpigmentation, but no issues yet)”
Positive
“Now:”
Positive
“Avene water spray Medicube TXA Serum”
Positive
Dupes & Alternatives
Anua
Azelaic Acid 10 Hyaluron Redness Soothing Serum
Better for Hyperpigmentation
3 shared traits
535 mentions
