TXA Niacinamide 15 Serum — Reddit Reviews
by Medicube
Updated September 16, 2026
Tranexamic acid and niacinamide target hyperpigmentation and brighten skin tone.
What the community says
A serum combining tranexamic acid and 15% niacinamide addresses dark spots and brightening. Reddit users find it promising for hyperpigmentation, especially when layered carefully. Studies show niacinamide can improve acne and redness but don't fully confirm its brightening potency here.
What this means for you
What people love
- High 15% niacinamide concentration with tranexamic acid for brightening
- Effective for fading dark spots according to multiple users
Watch out for
Product details
Skin type data limited
Where to buy
What the science says vs. what Reddit says
What the science says
Niacinamide
Some evidence for acne- It often improved acne, but many studies used niacinamide together with other ingredients
- 19 studies back this, including one large review
- Some studies found it worked about as well as clindamycin or benzoyl peroxide
- A few studies found niacinamide beat a placebo or no treatment for red, sore spots and blemishes
- No major side effects were reported in the findings given
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 17 mentions across 14 threads
Medicube TXA Niacinamide 15 Serum on Reddit, in one place — 14 threads from r/tretinoin, r/koreanskincare and 3 more, summarized.
“Apply Medicube TXA 15% Serum”
Positive
“I was very careful as I was also introducing Tranexamic Acid serum during the daytime to boost the hyperpigmentation fighting effects of the tret.”
Positive
“It has worked well for me though.”
Positive
“5. Medicube TXA 15%”
Positive
“The medicube TX serum is really good when paired with the toowongfoo for hyperpigmentation.”
Positive
“The medicube & twowongfoo are for the hyperpigmentation”
Positive
“I have some hyperpigmentation and started using medicubes TXA serum in the mornings.”
Mentioned
“Too soon to tell if it’s improving things but I’m hopeful.”
Mentioned
“I usually follow with medicube txa niacinamide and moisturizer.”
Positive
“Instead of the txa niacinamide, i used good molecules HA serum and mositurizer.”
Positive
“Did this for 2 months and it actually made the clogging worse.”
Positive
“Medicube TXA Serum (only introduced last week to deal with hyperpigmentation, but no issues yet)”
Positive
“Now:”
Positive
“Avene water spray Medicube TXA Serum”
Positive
“MediCube TXA Niacinamide 15% Serum”
Cautionary
“I agree I’d skip Medicube”
Cautionary
“I’d skip both the medicube and consider more hydration”
Cautionary
