TXA Niacinamide 15 Serum — Reddit Reviews
by Medicube
Updated August 18, 2026
15% niacinamide and tranexamic acid target hyperpigmentation and brighten skin tone.
What the community says
This serum combines 15% niacinamide with tranexamic acid for tackling dark spots and uneven tone. It often appears in active rotations, especially morning routines paired with tretinoin. Some users find it drying or pore-clogging, so watch for breakouts and consider hydration balance.
What this means for you
What people love
- High-dose tranexamic acid (15%) plus 15% niacinamide for targeted brightening and fading dark spots
- Commonly used as a morning active alongside tretinoin for enhanced hyperpigmentation results
- Lightweight serum texture that layers well under moisturizers and sunscreen
Watch out for
- Some users report increased dryness and recommend swapping for a more hydrating product
- Potential for clogged pores or worsening acne in sensitive or acne-prone skin
- Avoid mixing with glycolic acid or other strong actives in the same routine to prevent sensitivity
Product details
Skin type data limited
Where to buy
Real Reddit threads — 14 mentions across 7 threads
Medicube TXA Niacinamide 15 Serum on Reddit, in one place — 7 threads from r/tretinoin, r/koreanskincare and 2 more, summarized.
“Apply Medicube TXA 15% Serum”
Positive
“I was also introducing Tranexamic Acid serum during the daytime to boost the hyperpigmentation fighting effects of the tret. It has worked well for me though.”
Positive
“Hope this is of use to someone!”
Positive
“5. Medicube TXA 15%”
Positive
“The medicube TX serum is really good when paired with the toowongfoo for hyperpigmentation.”
Positive
“The medicube & twowongfoo are for the hyperpigmentation”
Positive
“I have some hyperpigmentation and started using medicubes TXA serum in the mornings.”
Mentioned
“Too soon to tell if it’s improving things but I’m hopeful.”
Mentioned
“I usually follow with medicube txa niacinamide and moisturizer.”
Positive
“Instead of the txa niacinamide, i used good molecules HA serum and mositurizer.”
Positive
“Did this for 2 months and it actually made the clogging worse.”
Positive
“Medicube TXA Serum (only introduced last week to deal with hyperpigmentation, but no issues yet)”
Positive
“Now:”
Positive
“Avene water spray Medicube TXA Serum”
Positive
“MediCube TXA Niacinamide 15% Serum”
Cautionary
“I agree I’d skip Medicube”
Cautionary
“I’d skip both the medicube and consider more hydration”
Cautionary
Dupes & Alternatives
Anua
Azelaic Acid Hyaluron Redness Soothing Serum
Better for Hyperpigmentation
3 shared traits
549 mentions