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Mela B3 Dark Spot Serum

HyperpigmentationSerum

Mela B3 Dark Spot Serum — Reddit Reviews

by La Roche-Posay

70nextscore25 verdicts

Updated October 3, 2026

Niacinamide-based dark spot serum for hyperpigmentation; mixed results, burning reports.

What the community says

Backed by 56 studies

A niacinamide-heavy dark spot serum people mostly reach for on melasma, post-acne marks, and stubborn sun spots. Redditors split hard: some see fading, others get burning or nothing after months, so YMMV if your skin is reactive or impatient.

From Reddit

Backed by 27 threads from r/SkincareAddiction, r/30PlusSkinCare and 3 more.

Read the threads ↓

What people love

  • Niacinamide-heavy dark spot focus
  • Can visibly fade stubborn pigmentation
  • Often layers fine in AM or PM routines

Watch out for

  • Burning and stinging show up in real use
  • Too many people report no visible change
  • Fragrance is a real snag for sensitive skin

Product details

Key Ingredients

Where to buy

What the science says vs. what Reddit says

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it on its own. See all 17 studies

    What the studies found
    • Most studies found niacinamide helped acne
    • It often cleared acne about as well as clindamycin
    • Some studies found fewer red, sore spots with 4% niacinamide
    • Some evidence was uncertain, and some studies found no clear difference
  • Hyperpigmentation

    Some evidence

    Niacinamide: 5 studies tested it on its own. See all 24 studies

    On Reddit: Niacinamide-rich serum shines for addressing dark spots with visible results after weeks of consistent night use. 11 mentions

    What the studies found
    • All of these studies found niacinamide helped fade dark spots or patches
    • Niacinamide 5% faded dark spots more than a placebo in studies of sun-damaged skin and dark patches
    • Used with salicylic acid peels, niacinamide improved dark patches more than peels alone
    • A niacinamide mix faded dark spots better than niacinamide alone in one study
    • One study found the fading effect reversed after niacinamide was stopped
  • Skin Barrier

    Not proven yet

    Few or mixed studies. This claim isn't established.

    Niacinamide: 1 study tested it on its own. See all 17 studies

    What the studies found
    • All studies found it helped the skin barrier
    • It lowered water loss through the skin
    • It made the outer layer of skin thicker

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 38 mentions across 27 threads

La Roche-Posay Mela B3 Dark Spot Serum on Reddit, in one place — 27 threads from r/SkincareAddiction, r/30PlusSkinCare and 3 more, summarized.

“and la roche posay mela b3 every morning”

Positive

“My skincare routine is basically cleaning my face with micelar water, effaclar by la roche posay and biretix every other day at night, and la roche posay mela b3 every morning.”

Positive

“I wear sunscreen every day.”

Positive

“PM: Cleanser (La Roche-Posay Toleriane) → La Roche-Posay Mela B3 serum → La Roche-Posay Cicaplast Gel B5”

Positive

“Open to hearing if this is doing anything useful for the post-AK redness/damage, or if I should be adding/swapping something.”

Positive

“Anything you'd add to or change about my current routine, or anything you'd specifically make sure to ask my derm about at my next visit?”

Positive

“La Roche Posay Mela B3 serum, then wait at least 3 minutes for it to absorb/dry”

Positive

“My skin has had near-zero post-tret peeling since I've started this regimen”

Positive

“Gentle tips that have helped me while re-implementing tret into my PM regimen”

Positive

“La Roche posay mela B3 serum works wonders for dark spots ..... Good luck babe!”

Positive

“Does anyone know what these brown marks are under my eyes and how I can get rid of them?”

Positive

“Hi! Does anyone know what these brown marks are under my eyes and how I can get rid of them?”

Positive

“[La Roche Posay Mela B3 serum ]”

Mentioned

“Evening:”

Mentioned

“Some examples of products that may help:”

Mentioned
82

“3. La Roche Posay mela B3 serum (for dark spot correction)”

Positive

“My skincare routine tonight is as follows”

Positive

“Everything but the pair acne cream is apart of my normal routine so I will know if the pair is the thing making the difference.”

Positive

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