Niacinamide Serum 12% Plus Zinc 2% — Reddit Reviews

• Acne

  Some evidence

  Niacinamide: 6 studies tested it on its own. See all 17 studies→

  Both ingredients for acne

  Niacinamide · Some evidence

  • Most studies found niacinamide helped acne
  • Some studies found 4% niacinamide cleared acne about as well as clindamycin
  • One study found 4% niacinamide improved red, sore spots, but IPL worked better
  • Some research found no clear difference, and a large review said the effects were uncertain

  Studied at 4–10% · this product: 12%

  Zinc · Not proven yet

  Few or mixed studies. This claim isn't established.

  4 studies tested it on its own. See all 16 studies→

  • The results were split, so there is no clear answer yet
  • Some studies found zinc helped acne when put on the skin
  • Used with clindamycin, zinc worked about as well as clindamycin alone
  • Used with erythromycin, zinc did not clear acne better than erythromycin alone

• Hyperpigmentation

  Some evidence

  Niacinamide: 5 studies tested it on its own. See all 24 studies→

  What the studies found

  • All of these studies found niacinamide helped fade dark spots or patches
  • In clinical trials, 5% niacinamide faded dark spots more than a placebo
  • It also helped when used with salicylic acid peels, more than peels alone
  • Used on its own, it helped, but one study found a niacinamide mix worked better
  • One study found the fading effect reversed after stopping niacinamide

  Studied at 2–10% · this product: 12%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.