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10% Niacinamide Serum

Serum

10% Niacinamide Serum — Reddit Reviews

by Skinlex

Not enough verdicts yetSee the Reddit discussion

Updated October 29, 2026

10% niacinamide targets post-inflammatory hyperpigmentation; benefits can be imperceptible.

What the community says

Backed by 69 studies

A 10% niacinamide serum aimed at post-inflammatory hyperpigmentation, with community interest around the higher-strength formula. It suits users who tolerate niacinamide, yet sensitive skin may react and some report poor absorption or no visible improvement.

From Reddit

Backed by 3 threads from r/scacjdiscussion, r/SkincareAddiction and 1 more.

Read the threads ↓

What people love

  • Frequently mentioned alongside tretinoin for PIH
  • Higher-strength 10% option versus 5%

Watch out for

  • 10% strength can aggravate niacinamide-sensitive skin
  • Several users saw zero visible benefit
  • Some users found it slow to sink in

Product details

Skin type data limited

Where to buy

Search on Amazon

What the science says

  • Acne

    Some evidence

    Niacinamide: 6 studies tested it directly. See all 17 studies

    What the studies found
    • Most studies found niacinamide helped acne
    • It often worked about as well as clindamycin when put on the skin
    • Some studies found it reduced red, sore spots and other pimples
    • Some research found the results were uncertain or showed no clear difference

    Studied at 4–10%this product: 10%

  • Skin Barrier

    Some evidence

    Panthenol: 5 studies tested it directly. See all 20 studies

    Both ingredients for skin barrier

    Panthenol Some evidence

    • All 5 studies that tested it directly found it helped the skin barrier
    • It helped skin hold more water and lowered water loss through the skin
    • Damaged or irritated skin showed less irritation and better healing signs
    • In people getting radiation, it delayed skin barrier worsening, though a steroid cream helped more

    Niacinamide Not proven yet

    Few or mixed studies. This claim isn't established.

    1 study tested it directly. See all 17 studies

    • The one study that tested it directly found it helped the skin barrier
    • It lowered water loss through the skin
    • It increased the thickness of the outer layer of skin

    Studied at 4–5%this product: 10%

  • Hyperpigmentation

    Some evidence

    Niacinamide: 4 studies tested it directly. See all 17 studies

    What the studies found
    • All 4 studies that tested it directly found it helped fade dark spots or patches
    • It reduced facial dark spots better than a moisturizer without niacinamide
    • Women with chloasma saw darker patches improve more when nicotinamide was added to salicylic acid
    • Studies also found facial skin looked lighter as dark spots faded

    Studied at 2–10%this product: 10%

  • Dehydration

    Some evidence

    Panthenol: 4 studies tested it directly. See all 7 studies

    What the studies found
    • All 4 studies that tested it directly found it helped dehydrated skin
    • It increased how much water the skin held
    • It helped the skin barrier recover and reduced water loss through the skin
    • It also reduced roughness and redness after irritation
    • It helped protect skin from irritation in healthy skin
  • Anti-Aging

    Some evidence

    Niacinamide: 2 studies tested it directly. See all 8 studies

    What the studies found
    • Both studies that tested it directly found it helped with signs of aging
    • It improved how firm and elastic the skin looked
    • It reduced wrinkles, uneven tone, redness, and yellowing
    • It helped skin hold more water and lowered water loss through the skin

    Studied at 2–5%this product: 10%

Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.

Real Reddit threads — 3 mentions across 3 threads

Skinlex 10% Niacinamide Serum on Reddit, in one place — 3 threads from r/scacjdiscussion, r/SkincareAddiction and 1 more, summarized.

“Skinlex 10% Niacinamide Serum: Ingredient list looks GREAT and some others seem to love it, but I saw absolutely zero niacinamide benefits for my skin.”

Cautionary

“I have also used the skinlex and not really noticed anything, not sure why.”

Cautionary

“Sometimes I feel like it doesn't sink in well, maybe that's the problem?”

Cautionary

“Skinlex 10% Extended Niacinamide, it has NAG which is really really good for pih”

Positive

“Skinlex has a niacinamide serum that I like”

Positive

“In that case, you'd want to a niacinamide/n-acetyl glucosamine product like Shark Sauce or Skinlex”

Mentioned

“Some people are sensitive to the higher 10% concentration so if you go that route, you might want to start with 5%.”

Mentioned

“If you don't see improvement with that, nacinamide alone probably won't be sufficient.”

Mentioned

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