
10% Niacinamide Serum — Reddit Reviews
by Skinlex
Updated October 29, 2026
10% niacinamide targets post-inflammatory hyperpigmentation; benefits can be imperceptible.
What the community says
A 10% niacinamide serum aimed at post-inflammatory hyperpigmentation, with community interest around the higher-strength formula. It suits users who tolerate niacinamide, yet sensitive skin may react and some report poor absorption or no visible improvement.
What this means for you
Backed by 3 threads from r/scacjdiscussion, r/SkincareAddiction and 1 more.
Read the threads ↓What people love
- Frequently mentioned alongside tretinoin for PIH
- Higher-strength 10% option versus 5%
Watch out for
Product details
Concerns
Skin type data limited
Where to buy
What the science says
Acne
Some evidence
Niacinamide: 6 studies tested it directly. See all 17 studies
What the studies found
Skin Barrier
Some evidence
Panthenol: 5 studies tested it directly. See all 20 studies
Both ingredients for skin barrier
Panthenol Some evidence
- All 5 studies that tested it directly found it helped the skin barrier
- It helped skin hold more water and lowered water loss through the skin
- Damaged or irritated skin showed less irritation and better healing signs
- In people getting radiation, it delayed skin barrier worsening, though a steroid cream helped more
Niacinamide Not proven yet
Few or mixed studies. This claim isn't established.
1 study tested it directly. See all 17 studies
- The one study that tested it directly found it helped the skin barrier
- It lowered water loss through the skin
- It increased the thickness of the outer layer of skin
Studied at 4–5%this product: 10%
Hyperpigmentation
Some evidence
Niacinamide: 4 studies tested it directly. See all 17 studies
What the studies found
- All 4 studies that tested it directly found it helped fade dark spots or patches
- It reduced facial dark spots better than a moisturizer without niacinamide
- Women with chloasma saw darker patches improve more when nicotinamide was added to salicylic acid
- Studies also found facial skin looked lighter as dark spots faded
Studied at 2–10%this product: 10%
Dehydration
Some evidence
Panthenol: 4 studies tested it directly. See all 7 studies
What the studies found
Anti-Aging
Some evidence
Niacinamide: 2 studies tested it directly. See all 8 studies
What the studies found
Research context, not treatment advice. Studies are about the ingredient, not necessarily this exact product.
Real Reddit threads — 3 mentions across 3 threads
Skinlex 10% Niacinamide Serum on Reddit, in one place — 3 threads from r/scacjdiscussion, r/SkincareAddiction and 1 more, summarized.
“Skinlex 10% Niacinamide Serum: Ingredient list looks GREAT and some others seem to love it, but I saw absolutely zero niacinamide benefits for my skin.”
Cautionary
“I have also used the skinlex and not really noticed anything, not sure why.”
Cautionary
“Sometimes I feel like it doesn't sink in well, maybe that's the problem?”
Cautionary
“Skinlex 10% Extended Niacinamide, it has NAG which is really really good for pih”
Positive
“Skinlex has a niacinamide serum that I like”
Positive
“In that case, you'd want to a niacinamide/n-acetyl glucosamine product like Shark Sauce or Skinlex”
Mentioned
“Some people are sensitive to the higher 10% concentration so if you go that route, you might want to start with 5%.”
Mentioned
“If you don't see improvement with that, nacinamide alone probably won't be sufficient.”
Mentioned





